228 resultaten
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
Lithium treatment potentially enhances survival and slows disease progression in ALS patients
Acute stress and increased levels of dopamine in the brain will lead to a shift from goal-directed behaviour to habitual behaviour. The shift will coincide with a change in functional connectivity between brain areas governing goal-direct and…
Vitamin K supplementation will lead to a deceleration of elastin degradation in COPD patients.
It is hypothesized that aerobic exercise therapy (AET) and cognitive behavioural therapy (CBT) are both effective in improving activities and QoL in patients with Amyotrophic Lateral Sclerosis (ALS) compared to the usual care.
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
1: Long term use of fluoxetine causes the excitability of the primary motor area of the brain to change 2: Long term administration of fluoxetine causes the muscle activation patterns to change
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
Saphenus blok reduceerd opname duur na epifysiodese van de knie - een triple blind superiority trial
We hypothesize that a single shot saphenous nerve block in combination with general anesthesia would be superior to general anesthesia alone regarding opiod consumption. pain scores. recovery and length of stay in adolecent patients undergoing…
Hypothesis is that elderly patients, acutely admitted for hip fracture, treated with melatonin for 5 days will experience less delirium than patients treated with placebo.
Compared to the control group, mother-infant dyads who practice at least one daily and continuous hour of skin-to-skin contact for the first five weeks after birth will show: Improved maternal outcomes 1. Mental health: 1.1 lower levels of…
The goal of the present study is to investigate whether the blockade of NA-transmission by beta-antagonist propranolol reduces the common EMDR effects (reduced vividness/emotionality of emotional memories) in order to find out if NA-release (evoked…
Oxytocin administration leads to stronger empathic reponses and faster emotional processing.
Vitamin D supplementation reduces the incidence of delayed union in fracture patients with a vitamin D insufficiency, compared to placebo.
This study hypothesizes that an oxytocin inhalation will increase prosocial behavior and reduces social anxiety during social interaction specifically in patients with SAD in comparison to a clinical and healthy control group.
We expect that treatment with azelastine/fluticasone propionate will decrease exercise tolerance limitation and will improve quality of life.
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.
This study investigates the hypothesis that regional anesthesia provided by wound catheter infusion (WCI) with ropivacaine reduces pain postoperatively (as measured with COMFORT behavior scale and NRS Pain scores) and leads to a morphine-sparing…
The present study will investigate how serotonin (manipulation via ATD) modulates psychological and physiological reactions to interpersonal stimuli in individuals at risk for MDD. This is relevant for several reasons: 1. The onset, severity, and…
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…