1923 resultaten
We hypothesise that one year compression therapy after DVT is equally effective as two years in the prevention of the post-thrombotic syndrome - in selected patients.
We hypothesize that breast cancer organoids will result in a prospective clinical model that is predictive of treatment response.
Case-management in ALS improves quality of life of ALS-patients and reduces the caregiver burden.
The main question of this study is, whether after standardized and quality controlled irradiation of the lateral nodes and selective LLND performed in a tertiary referral center, the lateral local recurrence rate in rectal cancers with lateral nodes…
We hypothesize that early mobilisation followed by additional protein intake is more effective in preservation of muscle mass than early mobilisation and optimal nutrition separately.
Clinical characteristics of psoriasis can predict the development of psoriatic arthritis.
Peripheral vascular disease (PVD) is a highly prevalent disease associated with significant morbidity and mortality. Current diagnostic procedures, such as duplex ultrasound examination, are not able to visualize the direct cause of the symptoms,…
There is a clinically and statistically significant difference in the percentage of patients who achieve and maintain clinical remission (defined as DAS < 1.6) and in functional ability and progression of radiological joint damage after 1…
Multiproblem families (MPFs) provide a huge public health challenge because of socio-economic deprivation, psychosocial problems, parenting problems, domestic violence and rule-breaking behaviour. Therefore, there is a strong need for evidence-based…
The type of implanted meshes has evolved steadily over the past few years in terms of material and fixation method. At the beginning, mainly fine-pored meshes (pore size <3 mm) with a high basis weight (up to 60 g / m2) and a 6-point fixation…
Participants who use the decision aid with benefit-harm assessment have a lower mean score on the decisional conflict scale than participants who use the existing decision aid.
In chronic pain the processing of sensational and painful stimuli will be disturbed. In patients with effective spinal cord stimulation the processing will normalize.
We expect patients treated with laparoscopic fenestration to have better clinical outcome; i.e. a lower PLD-Q score, compared to aspiration sclerotherapy, when measured 4 weeks after the procedure. We expect this difference to become smaller over…
In this study it is hypothesized that patients with a cochlear implant will benefit from an individual imaged based fitting that pursues natural hearing alignment and is implemented from the start of the rehabilitation process.
It is hypothesized that the surgical closure arm will result in an increased radiological fistula closure rate on MRI compared to the anti-TNF treatment arm (40 versus 15% respectively).
No formal hypothesis is set in this study. The sample size is based on feasibility considerations.
A short course of amoxicillin/clavulanic acid will not reduce the number of urinary tract infections in children that have been catheterized during a short period.
The pericapsular nerve group (PENG) block is superior to placebo 'sham' blocks in hip arthroplasty surgery in reducing patients pain scores (Numeric Rating Scale of 0 to 10), on the day of surgery
Through stress the mast cells become activated and by their vaso-active substances the mucosa permeability will become increased. Therefore the mucosa is easier to penetrated by microbes and acid. This increased permeability will leads to…
Our research objectives are two-fold: First we investigate whether nocebo effects can be learned via electrical pain conditioning and verbal suggestions. We expect that participants in the nocebo group, but not the control group, will report higher…