145 results
The aim of the RHINO trial is to compare the effect of parathyroidectomy and cinacalcet treatment on quality of life in end-stage renal disease patients with hyperparathyroidism and to evaluate cost-effectiveness. The aim of this pilot study is to…
To demonstrate safety and assess the clinical use and outcomes of the Lutonix® DCB for treatment of stenosis or occlusion of native below-the-knee arteries in a heterogeneous patient population in real world clinical practice.
In this phase I/II clinical study will assess the safety, effectiveness and homing of asCTMP, namely autologous mesoangioblasts, that will be injected 3x intra-arterially in right lower leg via catheter in 5 indivuals that carry the m.3243A>G…
We want to study the effect of glutamine on duration of mechanical ventilation and lenght of stay in ICU or hospital.With the availability of a Point of Care (POCT) measurement of plasma glutamine level a measurement can be performed short after the…
To study the effects of a 6-week unsupervised home-based exergaming training on the balance ability of older adults who have a fall risk or who have fallen without physical consequences.
The primary objective is to determine the efficacy of MagnetOs microstructured BCP granules in inducing adequate bone quantity and quality to support endosseous dental implants in the two-staged maxillary sinus floor augmentation procedure.…
The primary aim is to characterize the cerebrovascular and common carotid artery blood flow response to the cold pressor test (CPT). The secondary objective is to explore to potential differences in these cerebrovascular and carotid artery responses…
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
Primary Objective: to determine if lactate can be continuously and reliably measured by microdialysis in subcutaneous tissue in healthy volunteers
The primary objective of this study is to determine the efficacy of vitamin D supplementation on the severity of PN in patients with multiple myeloma.
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end of coronary angiography or PCI.
The objective of this study is to obtain physiological data on lung aeration during pulmonary transition in newborn infants.
The objectives of this study are to evaluate the safety and performance of the valve and delivery systems for the treatment of symptomatic moderate to severe degenerative or functional mitral regurgitation in a prohibitively high risk patient…
The primary objective is to identify additional genetic loci associated with skin fluorescence in patients with type 1 diabetes Mellitus. Secondary we want to assess if the identified loci are also associated to HbA1C, or if alternative loci are…
The aim of our project is to perform a novel mass screening to detect CD in 12 months-4 years old children who visit the YHCCs in a well-described region in the Netherlands, to show that it is feasible, efficient, cost-effective and well accepted by…
What is the correlation between intramuscular and surface EMG of the mm. multifidi in different clinical tests in healthy subjects and non-specific lower backpain patients?
The primary objective of this study is to evaluate the effect of inclisiran treatment on:•LDL-C levels at Day 510•Time adjusted percent change in LDL-C levels from baseline between Day 90 and Day 540 levels. The secondary objectives of this study…
Primary objectiveThe primary objective of this study is to evaluate the efficacy of bimekizumab in subjects with moderate to severe HS.Secondary objectiveThe secondary objective of this study is to assess the safety, tolerability, immunogenicity,…
To evaluate the safety and toxicity of ACT and low-dose IFN-alpha plus nivolumab according to CTCAE 4.0 criteria. Toxicity grade 3 or less and SAE related to treatment but that do not result in treatment termination are considered acceptable for…
The current study aims to replicate the Bohus study published in 2013, comparing the effect of a 12-week residential DBT-PE program on the severity of PTSD to that of a waiting list condition in patients who suffer from CSA related PTSD and from one…