1849 results
The objective of this cross-sectional study is to assess the relation between plaque characteristics, detected by Coronary Computed Tomography Angiography (CCTA) and Intravascular Optical Coherence Tomography (IVOCT), and the hemodynamic…
Objective(s): The primary objective of this study is to asses the dynamic vaginal pressure profile in two groups: 1) women diagnosed with dyspareunia and, 2) women with primary vaginismus. The secondary goal is to assess vaginal reflexes in women…
The primary objective of the study is to demonstrate the reduction of low-density lipoprotein (LDL) cholesterol (LDL-C) by REGN727 in comparison with ezetimibe (EZE) 10 mg PO QD after 24 weeks in patients with primary hypercholesterolemia (…
1. To reduce the time required for pre-exposure rabies vaccination of military personnel2. To reduce costs of pre-exposure rabies vaccination of military personnel 3. To obtain a non-inferior immune response to a shortened, low-dosed scheme compared…
Primary Objective:The primary objective in the current trial is to use graph theory to examine how the organization of the functional brain network may be altered by the administration of methylphenidate. The main question we intend to answer in…
In our current study we would like to evaluate a newly developed surgical platform for minimal invasive cardiothoracic surgery: the soft tissue expander. Main objective of the study is to determine the feasibility of creating a trans tissue expander…
Primary Objective: To determine if spinal and cortical balance control mechanisms mediate the age-associated decline inbalance skills.Secondary Objective: To determine the reliability of TMS and H-reflex measures in the soleus muscle in different…
To compare the number of responders to vaccination with pneumococcal and conjugated Hib vaccine at different time points after last dose of rituximab, to investigate what the ideal moment of vaccination would be. Secondly to study the immune-…
Evaluation of therapeutic safety and clinical efficacy of MSC transplantation in septic shock.
to combine and validate diagnostic tests for the identification of preclinical very early RA (VERA) patients and prognostic tests for the prediction of progression
The primary objective of this study is to assess the effect of individualizing the growth hormone dose versus standard treatment with 1 mg/m2/day on adult height and the first and five year growth response. Secondly, we want to assess the long term…
A Cross-sectional Study of Renal Function in Treatment-naïve, Young Male Patients with Fabry Disease
The objectives of this study are (1) to document renal function and other Fabry disease manifestations across age in treatment-naïve, young male patients with Fabry disease; and (2) to provide a reference group for comparison with interventional…
To investigate the feasibility of using L-PRP on anastomosis to prevent septic complications from occuring.
To demonstrate that percutaneous flexor tenotomy is an effective way to treat poorly healing ulcers in diabetic patients with hammertoes. We want to measure this effect by determining the healing time, percentage healed wounds and decrease in size…
The objective is to gain insight into the efficacy of bright light therapy for chronic sleep onset insomnia in children with ADHD, and to evaluate whether amelioration of the sleep problem results into improved cogntion and behavior as well.
Objectives1.3.1 Primary ObjectiveCompare the efficacy of BMS-945429 versus placebo for induction of clinical remission (defined by an absolute Crohn*s Disease Activity Index [CDAI] score < 150) at Week 8 (IP-57).1.3.2 Secondary Objectives•…
Core Study:Primary objective: • To demonstrate that the efficacy of E5501 (in addition to standard of care) is superior to placebo (in addition to standard of care) for the treatment of adult subjects with chronic immune thrombocytopenia (idiopathic…
To determine, in patients registered at our hospital having CRPS (types I) at the leg, the percentage of patients having clinical features compatible with SFN and compared to the unaffected leg (in unilateral cases) to determine possible focal or…
Objective of the study:Investigating with use of the classical coagulation tests on one hand and with the ROTEM on the other hand what is exactly becoming disturbed in the coagulaton because of bleeding during surgery of the aorta abdominalis,…
The aim of this study is to investigate the interobserver variation in assessment of acute posthypoxische myoclonus in patients after cardiopulmonary resuscitation.