2677 results
The main objective of this study is to compare the femur tunnel positioning after AMP, TLS and TT reconstruction techniques. We will also look at the relation between tunnel positioning and tunnel widening.
Primary Objective: To investigate whether differences exist in muscle function, muscle energy metabolism and cardiorespiratory fitness in CML patients with muscle complaints, compared to CML patients without muscle complaints, and controls (non-CML…
The primary objective is to determine the effect of dietary ribose supplementation on muscle function in patients with isolated LGMD as caused by a dystroglycanopathy. The secondary aim is to determine if ribose is well tolerated in this patient…
To determine which costimulatory and co-inhibitory molecules are expressed on tumor-infiltrating lymphocytes (TIL) derived from patients with CRC (including metastasized CRC), and to study the effects of targeting these molecules on their function…
The aim of the study is to assess the feasibility of conducting a definitive trial in terms of recruitment, use and acceptability of H@H, quality of care and the advantages and disadvantages of H@H in comparison to usual hospital care.
Lynch-related tumors mostly develop in the ascending right side of the colon (70-85%). Strikingly, it was recently discovered that dense bacterial biofilms and invasive bacteria occur in the colonic mucosa of 87% of right-sided colorectal cancer (…
1. We will perform an exploratory study using whole exome sequencing (WES) on SS MALT lymphoma samples to pick up specific gene mutations enriched or exclusively present in salivary MALT lymphoma in SS patients.2 .We will investigate the relation…
To evaluate the effectiveness of blood pressure (BP) home monitoring on the occurrence of hypertension, efficacy of BP treatment, QOL, health-related symptoms, work ability and life-style behaviour in women 40-60 yrs, after a previous PE in…
To investigate the potential of a novel dietary substrate preparation to enhance muscle mitochondrial function in GSD IIIa via acute nutritional ketosis. Secondary objectives are to further investigate in vivo exercise tolerance and intramuscular…
Primary Objective: To further optimize the IPMDSSecondary Objective(s): To determine in which age-groups the items within the IPMDS are appropriate To determine whether the IPMDS can assessed reliably by research nurses, students and physician…
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
Primary objectivesTo study if LcS can colonize the esophagus of BE patients.To study the effect of LcS colonization on the Gr+ (except for LcS)/ Gr- bacterial ratio of the esophagus.Secondary objectivesTo quantify the number of specific pathogenic…
To analyse serum sodium concentration, serum osmolarity and arterial bloodgas at different times before and after administration of HTK solution, to get more insight of the impact of this solution on these biochemical parameters and to improve our…
The primary aim is to characterize the cerebrovascular and common carotid artery blood flow response to the cold pressor test (CPT). The secondary objective is to explore to potential differences in these cerebrovascular and carotid artery responses…
Part 1: To develop a child friendly method to balance bilateral input with regard to loudness and to assess the effect of this so-called bilateral loudness balancing on speech perception in noise and localization. This child friendly method with…
Our objective is to investigate how complex finger movements like fast sequences are controlled by the brain. Muscle activation patterns, studied by multi-channel EMG on both intrinsic and extrinsic hand muscles, and force traces are compared…
to determine the prevalence and significance of chronic nephrotoxic effects of cisplatin therapy by 1) identifying patients with chronic cisplatin nephrotoxicity and 2) reviewing their QoL. Eventually, this could improve care in these patients
To perform a detailed non-invasive analysis of mechanical activation under different volume loading conditions and to describe the accompanying hemodynamic response.
Hypothesis: gaseous signaling molecules influence placental vasomotor activity to compensate for hypoxemia. Metabolites of these vasoactive molecules can be found in the blood and urine and can indicate whether this (compensatory) mechanism is used…
To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.