141 results
The objective of this cross-sectional study is to assess the relation between plaque characteristics, detected by Coronary Computed Tomography Angiography (CCTA) and Intravascular Optical Coherence Tomography (IVOCT), and the hemodynamic…
Objective(s): The primary objective of this study is to asses the dynamic vaginal pressure profile in two groups: 1) women diagnosed with dyspareunia and, 2) women with primary vaginismus. The secondary goal is to assess vaginal reflexes in women…
1. To reduce the time required for pre-exposure rabies vaccination of military personnel2. To reduce costs of pre-exposure rabies vaccination of military personnel 3. To obtain a non-inferior immune response to a shortened, low-dosed scheme compared…
Primary Objective:The primary objective in the current trial is to use graph theory to examine how the organization of the functional brain network may be altered by the administration of methylphenidate. The main question we intend to answer in…
Primary Objective: To determine if spinal and cortical balance control mechanisms mediate the age-associated decline inbalance skills.Secondary Objective: To determine the reliability of TMS and H-reflex measures in the soleus muscle in different…
Evaluation of therapeutic safety and clinical efficacy of MSC transplantation in septic shock.
to combine and validate diagnostic tests for the identification of preclinical very early RA (VERA) patients and prognostic tests for the prediction of progression
A Cross-sectional Study of Renal Function in Treatment-naïve, Young Male Patients with Fabry Disease
The objectives of this study are (1) to document renal function and other Fabry disease manifestations across age in treatment-naïve, young male patients with Fabry disease; and (2) to provide a reference group for comparison with interventional…
To investigate the feasibility of using L-PRP on anastomosis to prevent septic complications from occuring.
To demonstrate that percutaneous flexor tenotomy is an effective way to treat poorly healing ulcers in diabetic patients with hammertoes. We want to measure this effect by determining the healing time, percentage healed wounds and decrease in size…
Objective of the study:Investigating with use of the classical coagulation tests on one hand and with the ROTEM on the other hand what is exactly becoming disturbed in the coagulaton because of bleeding during surgery of the aorta abdominalis,…
Primary objective of this study is to investigate if the Metacognitive Reflection and Insight Therapy (MERIT) improves metacognitive abilities in people with schizophrenia. Secondary objective is to examine whether improvement in metacognitive…
Primary objective: To determine if unilateral exercise with the use of a mirror produces greater adaptations in the untrained limb than exercise without a mirror. Secondary objective: To determine corticospinal and cortical mechanisms of adaptations…
1.1 Primary ObjectivesDuring 12 weeks of treatment in subjects with active RA on stable DMARD therapy:• To evaluate the efficacy of VX-509 across a range of doses• To evaluate the early effect of VX-509 administration on joint structures as assessed…
To assess if preoxygenation with 100% O2 or preoxygenation with 100% O2 and PEEP are different with respect to the development of atelectasis as determined by lung computed tomography.
The purpose of this clinical investigation is to evaluate the effectiveness of modified Sensor designs on the longevity (up to a maximum of 90 days) of the Senseonics Continuous Glucose Monitoring (CGM) System. The investigation will also evaluate…
The study will evaluate the injection of AMDC for Urinary Sphincter Repair (USR) compared to a placebo dose, with the hypothesis that one or two treatments of AMDC is statistically superior to placebo at 12 months following the initial treatment.
Clarify the effect of 5T polymorphism with or without another CF causing mutation on the other allele, on the CFTR function.
The primary objective of this study is to determine the sensitivity of the fluorescent tracer bevacizumab-IRDye800CW using a NIR fluorescence endoscope ans spectroscopy probe in identifying adenomatous polyps during surveillance endoscopy in…
To suppress low-level viremia to a level below 50cp/mL in patients using cART by switching their current non-nucleoside reverse transcriptase inhibitor (NNRTI) or PI to DRV boosted with ritonavir (RTV) (DRV/r). Secondary objectives are to reduce the…