764 results
The results of the combined [11C] PIB and [18F] FDG PET patterns data and the clinical diagnosis are used in a multimodal, multitracer andmultivariate analysis approach to demonstrate regional and voxelwise correlations.
Primary Objective: We aim to investigate the possibility of erasing multimodal memories by applying repetitive TMS to a somatosensory region that represents part of the memory trace. Specifically, we expect that application of the stimulation…
With the proposed study we aim to gain insight into the effects of oxytocin (OT) on both parents* and grandparents* sensitive, empathic, and protective responses to their (grand)children, and in the neural origins of these responses.The primary…
Primary Objective: to ascertain whether tVNS affect performance (as measured by modulation of reaction times and/or error rates) in two cognitive tasks designed to examine PES and PIA, as well as specific components of pupillary response that will…
Protocol page 17The Mapping for Transvenous Phrenic Nerve Stimulation Study (MAPS) is being conducted to evaluate the feasibility of transvascular stimulation of phrenic nerves via an EP catheter advanced into the great veins.
Collection of skin tissue and blood samples from patients with mild to moderate psoriasis for efficacy testing of a new compound in a humanized mouse model.
To elucidate in the same participants (late chronotypes with at least two hours of social jetlag) the changes in sleep timing, social jetlag and endogenous circadian phase of melatonin with more than two hours of social jetlag shielded from blue…
The main objective of this study is to investigate the effectiveness of the self-help program compared to a waiting-list control group in reducing depressive symptoms. Secondary objectives include the investigation of moderators and mediators of…
To investigate the impact of the multispecies probiotic product Ecologic*Barrier on neurocognitive measures of emotion and executive functioning.
To assess the clinical and cost effectiveness of the anterior approach, compared to the conventional posterolateral approach for THA in terms of physical functioning and health-related quality of life
To develop TMS-EEG as a technique to study the interaction between brain regions. The specific experiments in this study are aimed at investigating the effects of brief activations of specific brain regions using TMS on signals recorded non-…
The primary objective of this study is to assess how selective attention to different food characteristics (calories, taste intensity and pleasantness) affects brain responses during tasting. Secondary objectives are to assess (1) whether taste…
The primary study objective is to investigate effects of conditioning on self-reported itch in healthy subjects in response to a short-term validated histamine test. Conditioning effects on other physiological and psychological parameters will be…
The primary objective of this study is to determine the equivalence accuracy of energy expenditure and resting heart rate measurement of newly developed software in reference to currently approved software. Secondary objective is to asses the…
This study will investigate the effectiveness of an interactive smart phone application that provides medication reminders and motivation to take up healthy activities during daily life, with the aim to improve schizophrenic and non-affective…
The primary objective is to investigate whether exogenous oxytocin administration enhances the placebo effect of positive suggestions as measured by subjective pain intensity and itch ratings in response to validated pain (Cold Pressor Test) and…
To investigate the effect of repeated exposure to different (novel) vegetable tastes in day care settings on children*s vegetable acceptance
Primary objective is to examine the effect of tryptophan supplementation on the number of accepted unfair offers in the Ultimatum Game. Secondary objectives are to examine the effect of tryptophan supplementation on the response bias in a social…
To better understand the utilities of the new BETACONNECT device and characterize its contribution to adherence, we plan to prospectively follow-up MS patients using the device for 24 weeks.
We aim to assess the neurocognitive mechanisms of tyrosine supplementation in older adults during different forms of cognitive control depending on the prefrontal cortex: working memory, reactive and proactive response inhibition, and effort…