1935 results
This research will explore how fast phonemic restoration of degraded speech can be learned. This will be done by training and testing normal-hearing listeners in several sessions with interrupted speech. We will also train a group of normal-hearing…
Objective(s): The primary objective of this study is to asses the dynamic vaginal pressure profile in two groups: 1) women diagnosed with dyspareunia and, 2) women with primary vaginismus. The secondary goal is to assess vaginal reflexes in women…
The present study will test 1) whether child pornography downloaders can be classified into four subtypes based on their social skills, mental disorders, sexual fantasies, sexual drive and own sexual abuse; 2) whether these offender types differ…
The family with the TRα2 premature stop enables us to investigate the biological role of the orphan wild-type TRα2 and the consequences of its dysfunction. The primary objectives of this proposal are (i) to search for a biological function of TRα2…
Determination of post-traumatic osteoarthritis in patients with a short follow-up period after ankle-surgery.
This study aims to detect differences in sick leave time, associated costs and quality of life between differentiated thyroid cancer patients treated in either a fast-track protocol or a traditional longer time interval between total thyroidectomy…
To investigate the dynamic changes in bone marrow adiposity during the menstrual cycle as assessed by Dixon*s Quantitative Chemical Shift Imaging (QCSI) measurements and to determine the role of estrogen in these changes.
The purpose of this study is to obtain information for the design of a method to measure the behaviour of the ascending and descending pathways of the nociceptive system.
The present protocol addresses these issues, with a systematic approach where we first assess optimal settings for BCI, and then test the quality of BCI application in adequately sized groups of subjects. The whole project is aimed at obtaining a…
Objective of this study is to determine validity, test-retest reliability and discriminant ability of the Mr Cube system to assess coordination and proprioception of the knee joint in patients following ACL reconstruction, patients with patellar…
To test the hypothesis that 6 months DAPT after second generation DES implantation in STEMI is not inferior to 12 months DAPT in terms of clinical outcomes (composite endpoint of all-cause mortality, any MI, any revascularization, stroke and major…
- To assess the burden of disease of congenital CMV infection in the Netherlands at the age of 5 to 6 years through the assessment of the occurrence of sensorineural hearing loss due to congenital CMV infection.- To establish the burden of disease…
The two primary objectives are to test the hypothesis that (1) structural and functional abnormalities of the fronto-striatal circuits are related to the development of compulsive and impulsive behaviour in ASD and OCD; and that (2) the glutamate…
Primary: To provide insight in the prevalence of diagnosed cases of IgG-subclass and/or antipolysaccharide antibodydeficiency in Dutch children. Secondary: To provide insight in the diagnostic process, the clinical presentation, the therapies used…
To examine the behavioural and neural effects of a single session of post-learning exercise on long-term memory retention in humans.
The main objective of this study is the clinical, physiological and psychosocial determinants of CAT in a broad sample of patients with moderate to very severe COPD and the impact of co-morbidities on the HRQL assessed with CAT. Secondary objectives…
We want to describe in detail the MTH-induced changes in pro- and anti-inflammatory markers in patients after CA. We further aim to evaluate the relation between neurological outcome and levels of pro- and anti-inflammatory markers.
The main objective of this study is to detect potential biomarkers for the differentiation of PD and DLB and the differentiation of PD subtypes by using neuroimaging.
The primary goal is to determine the degree of independent functioning of the patient with a proximal humeral fracture.A secondary goal is to evaluate all primary and secondary costs during the rehabilitation period after a proximal humeral fracture…
To evaluate in detail the functionality of immune cells in the liver and blood in chronic HCV patients before, during and after treatment with telaprevir, pegylated-IFN-alfa and ribavirin.