151 results
To determine the incidence of posttraumatic osteoarthritis following distal radius fractures in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
Primary: Assess the effect of i.v. infusions of BYM338 on muscle volume of the thigh (assessed by MRI) at 4, 8, 16 and 24 weeks, compared to placebo, in COPD patients with pulmonary cachexia.Secondary: Effect on 6-minute walk test, safety and…
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
Determination of post-traumatic osteoarthritis in patients with a short follow-up period after ankle-surgery.
The objective of this study is to obtain insight in the characteristics of sarcopenic versus non-sarcopenic community-dwelling older people.
To find out if intravenous MSC is a safe treatment for children with therapy-resistant JIA
To investigate the (cost) effectiveness of early ACL reconstruction (<6 weeks after injury), compared to the usual timing of ACL reconstruction (> 3 months after injury). Hypotheis is that early ACL reconstruction results in less loss…
Objective of this study is to determine validity, test-retest reliability and discriminant ability of the Mr Cube system to assess coordination and proprioception of the knee joint in patients following ACL reconstruction, patients with patellar…
The effects of cross-education on loss of muscle strength and knee function after ACL reconstruction
Primary Objective:The aim is to compare the effects of rehab with standard care vs. standard care plus XED on loss of muscle strength and function in the operated limb at the end of phase I rehab after ACL reconstruction surgery.
To assess the analgesic efficacy, safety, and tolerability of once daily orally administered GRT6005 in a total of 3 fixed doses (i.e., 200 µg, 400 µg, and 600 µg GRT6005) compared to placebo in subjects with moderate to severe chronic LBP.
To estimate the prevalence and burden of disease of PsA among PsO patients in primary care,.To test the ability of the PEST(1), the PASE(2) and the EARP(3) to detect cases with PsA in primary care.To develop an easy applicable prediction rule for…
The primary objective is to study the course of muscle (fiber) atrophy in elderly males and females with a fall-related hip fracture or elective hip surgery and the influence of additional nutritional support during hospital admission. Secondary…
The primary goal is to determine the degree of independent functioning of the patient with a proximal humeral fracture.A secondary goal is to evaluate all primary and secondary costs during the rehabilitation period after a proximal humeral fracture…
to combine and validate diagnostic tests for the prediction of clinical response to therapy with biologics in patients with reumatoid artritis.
The withhold of the use of a spinal orthosis for traumatic spinal fractures will lead to equal pain, radiologic outcome, and quality of life (QoL) in patients.
to combine and validate diagnostic tests for the identification of preclinical very early RA (VERA) patients and prognostic tests for the prediction of progression
To assess the diagnostic performance (sensitivity, specificity, ROC curve) of the bone SPECT/CT scans. To assess the intra- and interobserver variability of SPECT/CT in patients suspected of having UCH.
To demonstrate that percutaneous flexor tenotomy is an effective way to treat poorly healing ulcers in diabetic patients with hammertoes. We want to measure this effect by determining the healing time, percentage healed wounds and decrease in size…
•To characterize the natural history and progression of DMD to help inform the design of future studies•To capture biomarkers of safety and disease progression•To provide comparative data for the development of rare exons for which formal controlled…
Analysing the effect of a standardised gait correction program on gait parameters and clinical outcome in mild to moderate knee osteoarthritis.