1908 results
To determine the incidence of posttraumatic osteoarthritis following distal radius fractures in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
Primary: Assess the effect of i.v. infusions of BYM338 on muscle volume of the thigh (assessed by MRI) at 4, 8, 16 and 24 weeks, compared to placebo, in COPD patients with pulmonary cachexia.Secondary: Effect on 6-minute walk test, safety and…
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
Determination of post-traumatic osteoarthritis in patients with a short follow-up period after ankle-surgery.
The objective of this study is to obtain insight in the characteristics of sarcopenic versus non-sarcopenic community-dwelling older people.
To find out if intravenous MSC is a safe treatment for children with therapy-resistant JIA
The main objective of this project is to evaluate the effectiveness and cost-effectiveness of minimal interventional procedures as an add-on to a multidisciplinary pain program for patients with chronic mechanical low back pain who are referred to a…
Obtain information regarding the movement abilities and muscle strength in persons with several neuromuscular diseases, which can be used to develop a motion controlles arm suport for daily use and training of arm function.
In the present study we evaluate the change in quality of cartilage and bone as a result of KJD and of HTO. Based on the results of this pilot study, we will design a clinical study, with sufficient power, using the most promising sequences to…
To investigate the (cost) effectiveness of early ACL reconstruction (<6 weeks after injury), compared to the usual timing of ACL reconstruction (> 3 months after injury). Hypotheis is that early ACL reconstruction results in less loss…
Objective of this study is to determine validity, test-retest reliability and discriminant ability of the Mr Cube system to assess coordination and proprioception of the knee joint in patients following ACL reconstruction, patients with patellar…
To examine if a functional brace in the treatment of Unimalleolar Weber-B fracture results in a higher Olerud and Molander Score, less pain, better comfort, greater range of motion.
The effects of cross-education on loss of muscle strength and knee function after ACL reconstruction
Primary Objective:The aim is to compare the effects of rehab with standard care vs. standard care plus XED on loss of muscle strength and function in the operated limb at the end of phase I rehab after ACL reconstruction surgery.
To assess the analgesic efficacy, safety, and tolerability of once daily orally administered GRT6005 in a total of 3 fixed doses (i.e., 200 µg, 400 µg, and 600 µg GRT6005) compared to placebo in subjects with moderate to severe chronic LBP.
The follow-up study has two main research questions:o Is the treatment of early RA according to the COBRA-light schedule as effective (based on DAS44 score, ACR/EULAR remission criteria, HAQ score and the Sharp/van der Heijde score) as standard…
Primary Objective: To study the arginine-NO metabolism during fracture healing and dysfunctional fracture healingSecondary Objective(s): To investigate if differences or decreased arginine and NO concentrations in bone healing form a prognostic…
To estimate the prevalence and burden of disease of PsA among PsO patients in primary care,.To test the ability of the PEST(1), the PASE(2) and the EARP(3) to detect cases with PsA in primary care.To develop an easy applicable prediction rule for…
The primary objective is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of RA in subjects with active RA who are refractory to an anti-TNF Alpha agent. The secondary objectives are to assess the following…
The primary objective is to study the course of muscle (fiber) atrophy in elderly males and females with a fall-related hip fracture or elective hip surgery and the influence of additional nutritional support during hospital admission. Secondary…