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The purpose of this study is to determine whether there is a superiority in efficacy of the sequential combined treatment Traumafocused Therapy preceded by Well Being Therapy versus the control group. The control group receives interventions focused…
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
Microstructured BCP might be a suitable substitute to autologous bone graft in the sinus floor augmentation procedure
This evaluation does not have a hypothesis to be tested since it is intended to evaluate the workflow and usability of the new software solution, without prior defined performance criteria.
In the proposed project we evaluate the potential benefits and feasibility of including (a) a decision support system, ‘Clinical Rules Engine’ (CRE) and (b) patient preferences, using the ‘Outcome Prioritization Tool’ (OPT) in a comprehensive…
To determine the safety and tolerability and to assess the PK and performance of VB5-845D-800CW in healthy volunteers and patients
To compare patient reported health-related quality of life outcomes (PROs) between BRCA 1 or 2 gene mutation carries who choose breast surveillance or bilateral prophylactic mastectomy with immediate reconstruction.
Approximately 15 to 30% of thyroid nodules evaluated by means of fine-needle aspirate biopsy (FNAB) are not clearly benign or malignant. Patients with cytological indeterminate nodules (Bethesda III/IV) are often referred for diagnostic surgery,…
Monitoring patients at home using ThuisVisite (measurements of vital signs using a wearable and a videoconsult) is feasible and safe.
We hypothesize that a dual task (eye movements) during suicidal imagery retrieval will reduce the frequency of such imagery.
Enhanced endoscopic imaging, including high-definition white light endoscopy and virtual chromoendoscopy, alongside targeted biopsies provides an accurate and reproducible assessment of chronic atrophic gastritis disease extent and staging, when…
We hypothesize that treatment with pelvic physiotherapy in patients with a chronic anal fissure and concomitant pelvic floor dysfunction will result in an improvement of quality of life. We also aim to provide a management protocol for Pelvic floor…
RTX 1*1000 mg compared to a placebo controlled group leads to a higher proportion of patients in glucocorticoid remission at week 21 in newly diagnosed PMR patients fulfilling the Chuang-criteria
Patients that are treated with lorlatinib will have an impairment in speech, mood and several cognitive domains. With extensive testing, more impairments will be found than with CTCAE criteria alone.
The prevelance of FGID in patients with uncomplicated gallstones is higher compared to the general population
1) an early asthma diagnosis with the breath test will improve disease control, quality of life of children and parents, optimise treatment and thereby improve the prognosis of wheezing children. The use of the breath test will considerably reduce…
Following the implementation we expect an increase in number of patients receiving pain medication, an increase in analgesic dosages, decrease of PAIC scores. With regard to the process evaluation we expect good interrater reliability and a…
The reporting rate of adverse drug reactions upon use of anthroposophic medicinal products, as well as the reporting rate of serious adverse drug reactions, is low as retrieved from pharmacovigilance databases of German manufacturers.
washing-without-water is 1) equally or more emotionally and physically comfortable for persons being bathed in bed; and 2) equally or less physically demanding for persons providing the bed bath.
Endoscopic placement of fiducial markers in patients with gastric cancer is feasible and beneficial for patient position verification.