We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
Bron
Verkorte titel
Aandoening
Muscle protein synthesis
Potato
Milk
Ondersteuning
Onderzoeksproduct en/of interventie
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Uitkomstmaten
Primaire uitkomstmaten
Muscle protein synthesis rates
Achtergrond van het onderzoek
More than half of the total amount of dietary protein that is consumed by humans worldwide is of plant origin, with plant based proteins providing up to 80% of dietary protein consumed in less developed regions. With exception of soy protein, and a single study on wheat protein in healthy older men, there are no studies that have quantified the anabolic response to the ingestion of other plant based protein sources in vivo in humans. Greater sustainability and low cost of plant based protein sources provide us with many opportunities in the emerging markets. These notions likely explain the increasing interest in the potential of using plant-based protein sources in sports nutrition supplements. Previous studies indicate that potato tuber protein is superior to most major plant proteins, with its nutritive value approaching (87-94%) that of egg white. However, how well potato protein is able to support muscle protein synthesis and muscle reconditioning following exercise in humans remains unknown. Therefore, the objective of this study is to investigate the anabolic properties of potato protein ingestion at rest and following a single bout of exercise in healthy young males.
Doel van het onderzoek
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato protein does not differ from the ingestion of milk protein.
Onderzoeksopzet
Bilateral muscle biopsies at: 0, 120 and 300
Blood drawn at: -180, -120, -60, 0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240, 300.
Onderzoeksproduct en/of interventie
Single leg exercise, Milk versus Potato protein
Publiek
Philippe Pinckaers
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
0000000000000
philippe.pinckaers@maastrichtuniversity.nl
Wetenschappelijk
Philippe Pinckaers
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
0000000000000
philippe.pinckaers@maastrichtuniversity.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Male
- Aged 18-35 y inclusive
- BMI 18.5 – 27.5 kg/m2 inclusive
- Healthy recreationally active
- Having given informed consent
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Allergies to milk proteins
- Lactose intolerance
- Smoking
- Diagnosed diabetes
- Diagnosed metabolic or intestinal disorders
- A history of neuromuscular problems
- Arthritic conditions
- Any medications known to (or may) affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
- Participation in a structured progressive (resistance) exercise program
- Previous participation in a 13C amino acid tracer study within the last 1 year
- Excessive alcohol use (>3 consumptions per day)
- Drugs use in the last 3 months (or the test day needs to be scheduled minimal 3 months after last drugs use)
Opzet
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In overige registers
Register | ID |
---|---|
NTR-new | NL6964 |
NTR-old | NTR7152 |
Ander register | NL63936.068.17 : METC173053 |