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We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
A TCS is comparable to TCC and an effective treatment in neuropathic forefoot ulcer,
Bimanual performance is a prerequisite for the independence and participation of young children with Cerebral Palsy (CP). Home-based training programs may be a useful addition to centre-based rehabilitation programs to improve this bimanual…
We hypothesize that endoscopic combination therapy, including in- and excision of the stenotic fibrotic ring combined with steroid injections and bougie dilation, is more effective than standard repeated endoscopic bougie dilation.
- surgical treatment for CMC OA is effective in terms of pain, function and satisfaction - There is a relatively large group of patients with significant residual pain and functional impairment or deterioration of their complaints - Baseline factors…
First, it will be investigated which is the best diagnostic tool for imbalance in CP. Second, it will be determined whether balance training can promote balance control in CP, and whether the improvements will be maintained after a follow-up period…
No difference in range of motion at 12 months follow-up
Prevalence of PNH in selection of patients with DVT. Patients younger than 30 years of age. patients with DVT on unusual places.
We postulate that faecal microbiota transplantation (FMT) from obese donors in patients with cancer can improve satiety (appetite) and subsequently nutritional status. Secondly, FMT might restore the gut barrier function and hence reduce systemic…
Prolonged exposure to supraphysiological levels of GH and/or IGF-1 induces activation of innate immune responses, which might contribute to the long-term CV morbidity in acromegaly patients.
Nonclinical pharmacodynamic studies indicate that InO can be an effective therapeutic agent against B-lymphoid malignancies and support its clinical evaluation as a targeted therapeutic option for B-cell NHL and ALL. Inotuzumab ozogamicin (InO) is a…
We hypothesize a priori that the Dutch NAT: PD-HF will be a feasible and acceptable tool to identify palliative care needs in patients with CHF and will initiate appropriate management.
We expect to demonstrate that ctDNA can be reliably detected in patients with perihilar cholangiocarcinoma.
Investigate if Chronic Fatigue Syndrome patients show signs of neuroinflammation, compared to Q-fever Fatigue Syndrome (QFS) patients and healthy neighbourhood controls.
An outpatient multidisciplinary rehabilitation program with an additional Serious Gaming intervention component is more effective than an outpatient rehabilitation program without a Serious Gaming component for reducing health complaints in patients…
1. High school Freshman develop less positive attitudes towards substance use after participation in Fresh Start than high school freshman in the waitlist control condition. 2. Fresh Start is more effective when it is implemented at the beginning of…
analysis of the systemic (blood) and local (tumor tissue) immune parameters in patients with pancreatic cancer and during conventional therapies could reveal new insights in the interplay of these treatment modalities with the immune system and…
Cord Derived Dendritic Cell Vaccination directed against WT1 will prevent patients from relapse
DLB patients with concomitant Alzheimer-type pathology (identified by CSF analysis) will have a more severe disease course (with a faster cognitive decline, more prominent structural and functional changes in the brain)