695 resultaten
The purpose of this study is to determine whether there is a superiority in efficacy of the sequential combined treatment Traumafocused Therapy preceded by Well Being Therapy versus the control group. The control group receives interventions focused…
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
Microstructured BCP might be a suitable substitute to autologous bone graft in the sinus floor augmentation procedure
This evaluation does not have a hypothesis to be tested since it is intended to evaluate the workflow and usability of the new software solution, without prior defined performance criteria.
Negative association between anti-Xa and body weight; lower anti-Xa levels in higher body weigt. Positive association between anti-Xa and kidney function; higher anti-Xa levels in patients with renal dysfunction
the present study investigates whether Circadian adjusted LED-based (biodynamic) lighting improve cognitive functions, circadian rhytm, behavioral problems (apathy and agitation), Quality of life and mood (depression) in patiënts with moderate- to…
Xres5 image processing will allow for radiation dose or contrast concentration or radiation dose reduction while maintaining appropriate diagnostic image quality.
Evaluation of the safety and tolerability of AP3066 in healthy males
To know where the margin is close during surgery could be of great benefit for the patient and reduce the morbidity of the post-operative treatment. This will be done with the use of an optical tracer that targets the metabolic vulnerabilities that…
To test the safety and preliminary efficacy of a dual acute thrombolytic treatment consisting of a small intravenous (IV) bolus of alteplase followed by IV infusion of HisproUK against usual treatment with IV alteplase in patients presenting with…
Aim of the MANCO study is to establish for once and for all that monitoring the effect of heparin during NCVI is essential to ensure the individual patient of safe and tailor-made anticoagulation. Not measuring the effect of the administered heparin…
It is hopthesized that a multidimensional implementation approach with multiple interventions integrated in the usual care will improve physical behaviour during hospitalization
Addition of threedimensional breast ultrasound to the conventional diagnostic workup improves diagnostic accuracy in women referred from breast cancer screening with a BI-RADS 0 test result.
Neutralizing antibody titers after fractional dosing of yellow fever vaccine are comparable to standard dose vaccination, ten years after primary vaccination
Investigate the acute effect of beetroot juice (BRJ) and high nitrate vegetables (HNV) vs. nitrate depleted beetroot juice (placebo (PL)) on exercise tolerance and vascular function in participants with diagnosed peripheral arterial disease.
The aim of this study is to investigate the effect of a short-term experiential Schema Therapy (ST) protocol in individual adult outpatients with cluster C Personality Disorders (PD) on overall wellbeing. Secondary outcomes are attainment of…
The randomized controlled trial (RCT) will be performed at Karakter Child and Adolescent’s Psychiatric Hospital and will be implemented at all locations, spread out over three provinces in The Netherlands. The project aims: 1. To explore the…
End stage kidney disease (ESKD) ranks among the most severe chronic non-communicable diseases with an unmet medical need, given the high (between 10% and 20%) and stable annual mortality rates in ESKD patients treated with dialysis. Kidney…
To determine the presence or absence of central sensitisation in patients with Chronic Low Back Pain with radiation to the leg (CLBPr) and to determine the effect of segmental nerve interventions on central sensitisation.
In primary prostate cancer patients, the exisstence of lymph node metastases is associated with developmment of distant metastases and negatively associated with cancer-specific survival. The performance of an extended lymph node dissection (ePLND…