23 results
At least 90% of the subjects, with 95% confidence, will tolerate the test formula.
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
Critical illness, along with the lack of zeitgebers on the PICU environment, and iatrogenic influences like medication and procedures, results in disturbed circadian rhythms in critically ill children, which is important for their recovery.
A decrease in the incidence of central line-associated bloodstream infections in the investigational study group, compared to the control group.
The test product supports normal physical growth in healthy term infants
IV sildenafil is superior to iNO for the treatment of pulmonary hypertension in CDH newborns and should be considered as the drug of first choice in the future
To analyze the number of patients with (germline/somatic) actionable molecular aberrations in patients with relapsed/refractory pediatric tumors for whom no standard treatment or study protocol is available.
The aim of the Continuous versus Intermittent Nutrition in Pediatric Intensive Care randomized controlled trial (RCT) is to investigate a strategy of intermittent nutrition with a focus on an overnight feeding interruption period versus 24-hour…
We hypothesize that functional Near Infrared Spectroscopy (fNIRS), eye-tracking, Indirect Calorimetry (IC), the BOD POD, and Bio-Impedance Analysis (BIA) are feasible outcome measures for children with Angelman syndrome.
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
The main objective of this study is to analyze the effect of early (12 weeks corrected age) versus late (17 weeks corrected age) introduction of complementary food (weaning) on the prevalence of obesity at the age of 2 years in preterm infants.…
This study's first objective is to assess lung mechanics (measured with FOT) in mechanically ventilated infants, in the clinical practice of the NICU, with intermittent measurements during the entire period of mechanical ventilation. The FOT…
Presepsin as diagnostic marker for bacterial infection in young infants with fever of unknown origin
This study aims to evaluate the role of presepsin in the diagnosis of bacterial infections in young infants with fever of unknown origin.
To test whether performing a knee-to-chest flexion (KCF) manoeuvre is feasible directly at birth in infants born after elective caesarean section (CS) and leads to clearance of excess of lung liquid.Also safety parameters for mother and child will…
The main research objectives for the proof-of-concept study are to show the feasibility and safety of a daily cycle of feeding and fasting in critically ill children of different age-groups, that will trigger an adequate fasting response while…
The aim of the study is to collect video recordings which will be used retrospectively internally at Philips to test whether an algorithm can be used to measure the behavior and physiology of babies by using a camera and/or wearable. Development of…
The primary objectives of this study are:- Can EEnG measure colonic motility/activity?- Can EEnG be used to distinguish between healthy subjects and patients suffering from a colonic motility disorder.Secundary objective:- What is the…
Investigate whether, in a routine clinical environment across a number of centers, the fabian-PRICO can adequately maintain oxygen saturation, with minimal staff intervention.
To investigate the relationship between body composition and parenteral nutrition in children with intestinal failure at 6 months corrected age. The ultimate goil of this study is to optimize the treatment of children with intestinal failure by…
The primary objectives of this study are:1. to investigate the association between both conventional and alternative coagulation tests, and hemostatic complications, including bleeding and clotting complications in pediatric ECMO patients2. to…