172 results
Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.
Patient with incurable disseminated left-sided colonic cancer are better palliated by colonic stenting than surgery measured by hospital free survival in "good health"(WHO-score 0 or 1) Colonic stenting is cost effective in patients with…
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
Patients undergoing breast conserving surgery in combination with oncoplastic surgery are more satisfied with the cosmetic result and have a higher quality of life
The investigational formula will be equivalent to the control formula with regard to the postprandial blood lipid parameters.
Non invasive hemodynamic monitoring is as good as invasive monitoring
This study evaluates the beneficial effects of exercise training with or without oral anti-diabetic medication in patients with coronary artery disease (CAD): PCI or CABG in stable CAD, or post STEMI and post non-STEMI patients who have pre-diabetes…
Antipsychotics (haloperidol) can cause acute changes in cardiovascular functions, metobolic parameters and platelet aggregation in elderly patients.
Many employees who are sicklisted do not really know how to handle the situation. Simple and specific education and individually based instructions through a website can possibly solve or reduce this problem. Besides, the website contains a…
Oral ondansetron reduces the proportion of referred children to a (paediatric) emergency department when added to oral rehydration therapy compared to oral rehydration therapy alone.
To determine whether a strategy of invasive treatment (relative to continued medical treatment) of patients with type 2 diabetes mellitus, mild symptoms of stable angina pectoris, and documented myocardial ischemia lead to a decrease in cardiac…
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
About 10-15% of the population suffers from chronic insomnia. Structurally poor sleep can have unpleasant consequences for people's health and quality of life. Therefore, proper treatments are of great importance. Fortunately, Cognitive…
Vernakalant is superior to Amiodarone and rate control alone in the acute conversion of recent onset atrial fibrillation (AF) in critically ill patients admitted to the medical ICU.
Pain Rehabilitation Programs (PRP’s) are proven effective for patients with chronic musculoskeletal pain (CMP). Evidence about the relationship of dose on the effect of PRP however, is unavailable. We hypothesized that shortening PRP will not be…
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…