4199 results
The principal aims of the study are to assess: 1. The effectiveness of a 5 day treatment course in arresting/ resolving episodic knee arthralgia/ flaring knee pain.2. The relative effectiveness of a low dose (1200 mg/day) of lipid formulated…
Primary ObjectiveTo investigate whether ultrasound guided tumor resection succeeds gross total resection significantly more frequently, when compared with the conventional non-ultrasound guided tumor resection.Secondary Objective(s)To investigate…
The objective of the present trial is to investigate the safety of an allogenic tumor cell lysate loaded onto autologuous dendritic cells (AlloDen) in patients with malignant mesothelioma (MM). Heretoo we will perform a phase I study with a…
The main study parameter is the routine measurement of serum phosphate concentrations after 8 and 12 weeks. Other study parameters are compliance to phosphate binders and supplement-related complaints such as nausea, diarrhoea, flushing and itchness…
To determine whether computerized training procedures can lead to a decrease of aggression-related attention andinterpretation, and whether this reduces aggressive behaviors.
The primary objective is to determine the effects of dietary nitrate (beet root juice) on the microcirculatory profile in healthy adults. The secondary objectives are 1) to determine the effects of dietary nitrate on macrocirculatory parameters, 2)…
The study has 3 objectives: 1. Proving that this form of RCA does not increase the risk of bleeding while achieving a degree of anticoagulation of the extracorporeal system that is similar to that when using LMWH. When this study shows that citrate…
The aim of this study is to investigate the structure and the biological behaviour of the peritoneum, in relation to the specific growth of EOC on the peritoneum, in order to identify the component of the peritoneum that maintains the blood-belly-…
Primary Objective:To evaluate the effect and sustainability over time of behavioural treatment for sleep problems in children with AS on the actual hours of sleep and sleep behaviour of the children.Secondary Objectives:To evaluate the effect and…
Primary:To evaluate the clinical activity of GSK525762 in NUT Midline Carcinoma and other solid tumors.Secondary:Effect of treatment with GSK525762 on tumor growth and survival. Pharmacokinetics of GSK525762. Safety.
1) Is e-COGRAT usable within the ABI population?2) What are the patients* experiences with e-COGRAT?3) What are the therapists* experiences with e-COGRAT?4) What changes in the e-COGRAT are necessary?5) Does this pilot with e-COGRAT show a decline…
Primary objective: To evaluate the effects of eHealth therapy and usual care in IBD patients with arthralgia and to compare the effects of eHealth interventions plus usual care with just usual care in IBD patients with arthralgia.
Primary Objective: Assessment of a group difference in clinically important improvement in functional outcome of at least 10 points as measured by the DASH questionnaireSecondary Objective(s): 1. To determine if there is a group difference in…
Primary:• To prove the superiority of a 12-week add-on treatment with 3.2 g/daygastro-resistant phosphatidylcholine granules (LT-02) in at least one of twodifferent dosing regimens versus LT-02 placebo for the induction ofremission in patients with…
Concluding, the aim of current study is to show feasibility of the MaMaLoc technology for surgical localization of clinically occult melanoma lesions, as well as to show feasibility of the MaMaLoc technology for lymph node detection, both in the…
To evaluate the efficacy of VX-661 in combination with ivacaftor through 24 weeks of treatment in subjects with cystic fibrosis (CF) who are homozygous for the F508del mutation on the CF transmembrane conductance regulator (CFTR) gene.
To evaluate the efficacy of HDM-SPIRE in the reduction of symptoms and the use of allergy rescue medication associated with HDM allergy in subjects with clinically relevant symptoms.
Primary objective is to examine the effect of tryptophan supplementation on the number of accepted unfair offers in the Ultimatum Game. Secondary objectives are to examine the effect of tryptophan supplementation on the response bias in a social…
This monocenter randomized controlled trial aims to compare postoperative outcomes of a laparoscopic valvuloplasty with a Toupet fundoplication in patients with GERD with a maximum hiatal hernia of 3cm. In addition, an economic evaluation of the new…
The study is designed to substantiate the efficacy of CCM in the heart failure population with ejection fraction ranging between 25 and 45%. The study is designed in an adaptive manner to ensure proper statistical significance and power of the…