7521 results
Primary Objective:To evaluate the effect and sustainability over time of behavioural treatment for sleep problems in children with AS on the actual hours of sleep and sleep behaviour of the children.Secondary Objectives:To evaluate the effect and…
Primary objective: - 50% seizure reduction or more at 3 months of dietary treatment .Secondary objectives: -level of ketosis on KD and MAD.-number of patients maintaining >50% seizure reduction on MAD.-number of withdrawals (not able to…
Primary Objective: Prediction of PCI with DWI MRI, using the surgically determined PCI as the reference standard.Secondary Objective(s): - MR Protocol optimisation- Comparison of the diagnostic performance of DWI-MRI in assessing the PCI with the…
To evaluate the impact of electroencephalographic NarcotrendTM Index (NI) monitoring on the speed of emergence and recovery from PPS for PGE.
To document that 8 weeks treatment with ledipasvir-sofosbuvir is effective in chronic HCV genotype 4 patients without cirrhosis.
To evaluate the efficacy of VX-661 in combination with ivacaftor and ivacaftormonotherapy through 8 weeks of treatment in subjects with cystic fibrosis (CF)who are heterozygous for the F508del mutation on the CF transmembraneconductance regulator (…
This proof of principle study is designed to study the excretion of two well-studied transporters, Aquaporin-2 (AQP-2) and the sodium chloride cotransporter (NCC), in urinary exosomes. Both are sensitive to water homeostasis, so that during water…
Studies examining the effect of couple therapy or couple-based interventions in treatment for personality disorder are very scarce and more research is required. Therefore, the present study examines the effect of couple-based interventions in…
In this study we would like to study the effects of the selective angiotensin II antagonist Telmisartan on inflammation and cell/matrix homeostasis in the human aneurysm aortic wall.
The aim of the present study is to study Metvix® photodynamic therapy (MAL-PDT) of superficial basal cell carcinoma (sBCC) using two light fractions with one or two hours interval: comparison of illumination at 3 (20 J/cm2) and 4 hours (55 J/cm2)…
The primary aim is to study colon motility following rectal resection with the construction of a deviating ileostomy in patients that received an enema as bowel preparation. We hypothesise that CTT is halted or decreased, similar as in patients that…
Our primary objective is to develop an easily assayable germline-based panel of biomarkers to aid in selecting prostate cancer patients for management with active surveillance. As a secondary objective, we tend to incorporate potentially promising…
To investigate the feasibility and utility of indocyanine green fluorescence imaging for intraoperative perfusion assessment in patients undergoing gastro-intestinal surgery, primarily measured by the number of intraoperative changes in operation…
The primary objective of this study is to get insight into the course of personality disorders in order to be better able to inform patients about their prognosis. We aim to identify factors associated with lower QoL and higher societal and medical…
Reducing the number of readmissions in the revolving door patients diagnosed with COPD by means of an outreaching care nurse.
The purpose of the sub-study is to do research into markers which will hopefully assist to diagnose the condition Peripartum Cardiomyopathy as early as possible. The blood donated for research will also assist in the assessment of women having a…
To establish the changes in tumour diffusion hyperthermia induces in humans.
The effectiveness of psychotherapy can be improved by increasing the frequency of sessions at the beginning of therapy. In addition, understanding processes that account for therapeutic change might enable us to optimize treatments.
To determine the sensitivity and specificity of IRT to detect clinical active arthritis in hand-joints of patients with RA or PsA using clinical examination and ultrasonography as gold standard.
We here wish to apply new advancements in multi-color flow cytometry for a detailed and sensitive examination of mast cells in peripheral blood of patients with SM.