107 results
Primary objective: determine whether HAPTOS intervention results in earlier attainment (postnatal days) of full enteral feeding and/or full oral feeding (postmenstrual age) compared to standard care. Secondary objectives: To determine whether Haptos…
The primary objective of the study is to examine the effects of group SFT for an out-patient ED population, as assessed by change in both ED pathology as in core self-beliefs. Hypotheses:1. There will be a decrease in dysfunctional core self-beliefs…
The primary objective of this study is to investigate the local tolerability of isoniazid inhalation by wet nebulization at ascending dosages. Secondary objective is systemic pharmacokinetics of inhaled isoniazid compared to intravenous dose…
The primary objective is to evaluate if and to what extend replacing all meat products in an average Dutch diet with currently commercially available PBMAs affects the systolic blood pressure of middle aged men and women in a 2x8 week fully dietary…
We aim to confirm that Maastro endoluminal HDR contact brachytherapy boosting is feasible and may increase the chance of functional organ sparing of the rectum in patients with rectal cancer.
The major objective of this clinical investigation is to demonstrate safety and effectiveness of the ablation system (OMNYPULSE* Bi-Directional Catheter and TRUPULSE* Generator) when used for isolation of the atrial PVs in treatment of subjects with…
The primary objective is to execute a feasibility study of the ELFI Health lifestyle intervention for three months in people with prediabetes in primary care (based on HbA1c). The secondary objectives are assessing the impact of the ELFI health…
The aim of the study is to investigate whether SI-NETs can be visualized with indocyanine green (ICG) and near-infrared (NIR) fluorescence imaging (FLI).
The primary objective is to investigate which of the four suturing techniques (Monocryl Smooth Suture, Vicryl Rapide Suture in combination with Indermil Skin Glue, Dermabond Prineo Skin Closure System, Stryker Zip Skin Closure) shows the least…
To investigate whether a reduction in social jetlag for 3 weeks can improve glycemic and metabolic control, sleep, mood and quality of life in people with (pre)diabetes.
The objective of this clinical investigation is to evaluate the safety and performance of the BeGraft Aortic covered stent Graft System & the BeGraft Peripheral covered stent Graft System (Bentley Innomed, Hechingen, Germany) in CERAB…
1. To evaluate the feasibility of cryoballoon therapy in patients with incurable esophageal carcinoma and symptoms of dysphagia, defined as technical success rate. In addition, the efficacy and safety will be assessed by looking at the clinical…
Primary Objective: What is the residual heparin concentration in autotransfusion system product in cardiothoracic surgery? Secondary Objective(s): 1. What is the outcome of the anti Xa determination? 2. How much residual heparin concentration does…
The aim of this study is to investigate whether a minimally-invasive stepwise treatment leads to sufficient improvement of forearm rotation in patients with malunion after fracture of the radius and/or ulna.
This is a first-in-human Phase Ia/Ib, open-label, multicenter, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-tumor activity of RO7502175 as a single…
To determine whether sensitivity towards NAC varies during different phases of the menstrual cycle in breast cancer patients.
The overall aim is to unravel the (patho)physiological mechanisms and potential clinical benefits of a pre-specified early switch from controlled to assisted ventilation. The primary objective is to investigate the changes in regional lung stress…
To study if an online brief CBT intervention is effective for anxiety and depression compared to care as usual (CAU) in patients with PCOS
: To investigate whether the omission of surgical gowns during CTR and TVR surgeries af-fects postoperative wound infections
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last six weeks prior to…