83 results
Primary Objective: To assess the hemodynamical effects of administration of AS in FGR fetuses and to compare these effects with those that occur in appropriate for gestational age (AGA) fetuses. Secondary Objective(s): To investigate the effect of…
The objective of this study is to assess the safety and feasibility of WATS for esophageal sampling after nCRT in patient with esophageal cancer.
The study primary objective will consist of assessing the safety and tolerability of single IV (bolus + infusion) doses of glenzocimab in patients with an acute ischemic stroke administered on top of the best emergency standard of care (including…
Objective: To show the protective value and to measure cost effectiveness of higher Ig dosing on progression of lung disease in PAD.
To explore innate immune cell composition, function and proliferation in the circulation, bone marrow, and atherosclerotic plaque in patients scheduled for elective carotid endarterectomy because of recent ischemic stroke or transient ischemic…
To determine FRAME-001-specific immune responses in peripheral blood after administration of FRAME-001 to patients with advanced NSCLC.Secondary objectives- To assess safety and tolerability of FRAME-001.- To evaluate clinical anti-tumor response to…
Measuring tFUS-dependent changes in behaviour (in our target tasks) when targeting deep brain regions [Behavioral Objective]
The main aim is to study whether fNIRS can measure cortical activation during pelvic floor muscle contraction and to study whether it is a reliable non-invasive alternative to invasive pelvic floor EMG in order to provide biofeedback during pelvic…
There are three main objectives in this study. The first objective is to compare online and offline CSO based on their psychopathic traits, narcissism and other personality dysfunctions. The second objective is to further investigate the more…
The objective of the proposed study is to determine the effectiveness, safety and cost-effectiveness of a strategy of cefuroxime combined with short course treatment with aminoglycosides compared to a strategy of ceftriaxone monotherapy in patients…
The ability to fuse discrete small molecules with different types of pharmacologic activity has created remarkable opportunities in drug discovery and development. Bendamustine itself is a fusion molecule of the nitrogen mustard mechlorethamine and…
Primary-To evaluate the safety and tolerability of a single dose of EDIT-101 when administered to participants with LCA10-IVS26 mutationSecondary-To evaluate different doses of EDIT-101 for subsequent clinical evaluation-To evaluate the efficacy of…
- In silico definition of the most optimal posaconazole dose for children and adolescents with CF aged 8 to 17 years.- Assess the prevalence of Aspergillus infection in children and adolescents with CF aged 8 -17 years.- An intensive sampling…
The objective of this study is to evaluate the safety and performance of the DaVingi* TR System for the treatment of patients with functional tricuspid regurgitation within its intended use.The study will:• Evaluate the safety and feasibility of…
To assess the effect of treatment with 100 mg of FAB122 (edaravone) on disease progression in patients with ALS.
To explore whether structural and functional brain markers of somatosensory deficiency acquired 3 weeks post-stroke could have an added value in predicting arm-hand capacity recovery 12 and 26 weeks after stroke compared to prediction based on…
The main objective of study 20190530 is to estimate the efficacy of Apremilast compared to placebo in the treatment of oral ulcers in pediatric subjects from 2 to < 18 years of age with oral ulcers associated with BD through week 12. See…
Study A: Validation of productive infection of RSV CHIM Study B: Effectiveness and immunogenicity of local administration of palivizumab on prevention of experimental RSV infection
Primary objective:To assess whether the state of premature immune aging (senescent CD8+ T cells) predicts treatment response to physical endurance intervention therapy in depressed patients. We will compare the mood-beneficial effects of physical…
The current prospective observational study proposes to use intra-patient comparisons of periods without and with contrast to elucidate the relationship between renal function and contrast administration in this population. The central question is:…