1027 results
To assess the provoking effect of partial sleep deprivation on paroxysmal neurological events in a EMU setting, in people with possible epileptic seizures.
Primary Objectives: * To determine if NA patients have altered cerebral activity related to motor planning of their affected arm compared to healthy controls and compared to their non-affected arm.* To determine if specific rehabilitation focused on…
1.1 Overall Aim: To establish a safe, standardized protocol for the perioperative management of patients with atrial fibrillation (AF) who are receiving a novel oral anticoagulant (NOAC) drug, either dabigatran, rivaroxaban or apixaban, and require…
This project aims to determine the validity of a home-based continuous bradykinesia assessment using free typing behaviour analysis. Secondarily, we aim to capture the presence of sequence effect in Parkinson's Disease patients using a computer…
The aim of this proposal is threefold: (i) test a neuroscientific model of prosocial development by relating neuroscience discoveries to changes in several dimensions of prosocial development in a comprehensive study including children, adolescents…
In this study, the aim is to perform a clinical evaluation of the NovioMini in children during behavioural bladder training to examine the performance of the NovioMini as a full-bladder-based notification system during natural bladder filling.
(1) To compare adenoma miss rates (AMR) between Endocuff Vision-assisted colonoscopy (EAC) and conventionalcolonoscopy (CC)(2) To compare adenoma detection rates (ADR) between EAC and CC(3) To assess whether a proposed increased ADR and reduced AMR…
The main objective is to identify the source of the *musician effect*, particularly for speech perception. The underlying processes involved and individual differences in different groups of participants in speech and music perception, both in quiet…
1) To evaluate changes in microvascular resistance of the infarcted area in the first hours after ST-elevation myocardial infarction and during the recovery period (<5 days)2) To classify patients according to recovery of microvascular…
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
Objective: The primary objective of this study is to investigate whether pain experience decreases or increases when cognitive functions decline in patients with Parkinson's disease. Furthermore will be investigated whether this is influenced…
Aim of this pilot study is to determine which intervention groups are feasible in a larger trial which aims to a compare postoperative pain and complication rates in moderate versus deep neuromuscular blockade, and normal versus low intra-abdominal…
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
The aim of this study is to investigate the effects of DMF (Tecfidera) on the association between fatigue and fatigability measures in pwRRMS starting with DMF medication.
The aim of this pilot study is to assess the effect of low intensity mastication training in patients with a mitochondrial disease on masticatory performance, efficacy, endurance, bite force and the feasibility of this training .
Primary Objective: To determine the safety and tolerability of NF135.C10 sporozoite immunization under chemoprophylaxisSecondary Objectives:• To determine the dose-dependent protective efficacy of NF135.C10 CPS-immunization against homologous…
The main objective of this study is to investigate the effect of cerebellar tDCS on impulsivity in healthy adults.
Measuring cardiac output using TTE with and without the use of ProbeFix in adult Intensive Care patients in which a PLR test is used as a fluid challenge. The possible changes in cardiac output measured with TTE are compared with the measurements…
This trial will prospectively test the use of ultrasound imaging and pleural fluid analysis in improving the management of patients with malignant pleural effusion.Primary objective: Establish if the use of TUS before and during the first 24-72…
Gaining an objective insight in muscle fatigue during exercise for patients with FSHD by 1. comparing the timing of change in sEMG amplitude and sEMG median frequency, to gas exchange variables, heart rate, work load and blood lactate levels during…