4807 results
Given the significant number of patients with OIPN and the possible prophylactic properties of venlafaxine, this study is designed. This study will consist of a randomised placebo-controlled clinical trial to study the prophylactic effect of…
We propose to conduct a randomised phase III trial evaluating a maintenance strategy comparing hepatic arterial injection of Yttrium-90 resin microspheres plus continuing simplified chemotherapy with/without targeted therapy (bevacizumab, or…
The aim of this study is to investigate the effect of ARTISS compared with our standard care on total volume of donor site seroma after harvesting a LD in immediate breast reconstruction. Seroma is diagnosed, when >= 20 mL can be punctuated…
The primary objective is to get a comprehensive insight in the role of body composition features in RCC, and how these are related to patient-, tumour- and lifestyle-related factors, circulating biomarkers, and recurrence and survival.The research…
To evaluate efficacy of topical treatment with coal tar compared to topical treatment with corticosteroids in children aged 1 to <16 years with moderate to severe AD, based on the percentage change in Eczema Area and Severity Index (EASI) at…
Collect data in an observational study on outcomes of endovascular fistula creation using the everlinQ endoAVF System
The aim of the RHINO trial is to compare the effect of parathyroidectomy and cinacalcet treatment on quality of life in end-stage renal disease patients with hyperparathyroidism and to evaluate cost-effectiveness. The aim of this pilot study is to…
To demonstrate safety and assess the clinical use and outcomes of the Lutonix® DCB for treatment of stenosis or occlusion of native below-the-knee arteries in a heterogeneous patient population in real world clinical practice.
Primary objectives: To evaluate the expression of inflammatory cytokines in HS lesional skin at week four (t=4) and week sixteen (t=16): - of subjects receiving apremilast compared to subjects receiving placebo;- within both groups relative to…
The aim of this study is to compare the effect of a postoperativenegative pressure dressing (Prevena (TM) IMS) with a standardwound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in low riks and high…
To assess real world experience with HeartMate PHP post CE Mark approval in supporting patients who are hemodynamically unstable, or at risk of being hemodynamically unstable, while undergoing complex percutaneous coronary interventions (PCI).
The purpose of the study is to examine how the Minicare I-20 fits into the ambulance workflow. Relevant process data of the ambulance workflow was collected (stage 1) looking specifically into chest pain patients. This second stage will focus on…
Primary Objective: To investigate the differences in microbiota composition in the upper GI tract between lean and obese subjects. Secondary Objectives: To compare the total bacterial count measured by qPCR in SI samples of lean versus obese…
The primary objective of the study is to assess the safety and performance of Akesys Prava Sirolimus Eluting Bioresorbable Peripheral scaffold system (Akesys Prava
The aim of this pilot study is to validate potential biomarkers which diagnose patients who will benefit from asthma treatment with macrolide therapy by using non-invasively collected body fluid specimens. Th1/Th2/Th17 patterns in patients suffering…
Primary objective:To establish four healthy donors for future CHHI studies
This is a pilot pretest-posttest intervention study to first test feasibility of an intensive, personalized, integrated training program consisting of disease-specific education, in combination with physical exercise and mental coaching in order to…
To determine the effect of RIPC on MINS in patients after pancreatic sugery.
The aim is to test whether EM in EMDR contributes to a reduction in dysfunctional beliefs about recalling the traumatic memory. A sample of Dutch veterans diagnosed with PTSD will be tested. During three EMDR treatment sessions we will measure…