1162 results
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
Dental caries lesions (with ICDAS Codes 3 and 4) can be treated by sealing, offering a less invasive and less costly treatment option with the same results as preparation and restoration of the carious lesions.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
Het doel van de studie is om op de consultatiebureaus in de regio Kennemerland de haalbaarheid, kosten-effectiviteit en acceptatie van vroege opsporing naar coeliakie (door middel van case finding) bij kinderen tussen de 12 maanden en 4 jaar te…
H0= Postprandial muscle protein synthesis rates do not differ between the 2 intervention groups (P>0.05) H1= Postprandial muscle protein synthesis rates differ between the 2 intervention groups (P<0.05)
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
The is that receiving Health Potential, in combination with a current health status check, the Stofberg Health Check, will lead to greater improvements in behaviour change compared to receiving the Stofberg Health Check only.
Primary sclerosing cholangitis (PSC) is a severe liver disease of unknown etiology leading to fibrotic destruction of the bile ducts and ultimately to the need for liver transplantation (LTx) in young adults. When PSC develops before the age of 13…
The constantly increasing number of aorto-iliac lesions in patients with end-stage renal disease (ESRD) seems to be the result of three main factors: increased recipient age, frequent atherosclerosis accompanying with end-stage renal disease and…
Submucosal irrigation with the Gum Irrigator will reduce bleeding on probing, pocketdepts and the amount of anearobic bacteria in the non-surgical treatment of peri-implantitis.
- It is hypothesized that a tailored, outreaching and systemic intervention promotes medication adherence - It is hypothesized that a tailored, outreaching and systemic intervention has a beneficiary effect on other medical as well as psychological…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
(Experimental) participants who receive information about the availability and use of mindfulness-apps after an MBSR course: (1) report higher frequency of mindfulness practice, (2) report higher mindfulness, lower general psychopathology, and…
We hypothesize that the course of the disease can be shortened with MUA with a quicker functional recovery and gain in range of motion and a subsequent faster return to work compared to conservative treatment.
To compare the resection speed of two different devices for removal of polyps (≥8mm - ≤20 mm) in terms of efficiency and complications.
We hypothesize that the associations between biopsychosocial factors and post-TBI sleep complaints and fatigue change over time., i.e., that the associations with biological factors are strongest in the first six months and then decline, whereas the…