3088 results
Aim of this study is to investigate the tolerance and the outcome of extreme hypofractionated RT for prostate cancer by delivering a high dose using two alternative time schedules, a short and long treatment interval.
a. By this research a treatment protocol for NET will be quantitatively and qualitatively evaluated on its effects. b. With the research findings it is possible to identify subgroups within the research population and indicate who benefits most from…
To determine the incidence of posttraumatic osteoarthritis following distal radius fractures in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
Primary: Assess the effect of i.v. infusions of BYM338 on muscle volume of the thigh (assessed by MRI) at 4, 8, 16 and 24 weeks, compared to placebo, in COPD patients with pulmonary cachexia.Secondary: Effect on 6-minute walk test, safety and…
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
Objective: To compare the in vivo pressure responses of air-charged catheters with water filled catheter systems pressure responses during standard cystometry.
Primary Efficacy Objective:• To evaluate the efficacy of tocilizumab (TCZ) compared to placebo, in combination with a26-week prednisone taper regimen, in patients with giant cell arteritis (GCA), as measured by the proportion of patients in…
Measurement of yellow fever vaccine efficacy; is 10 years the right point in time for revaccination?
Objectives:1) By measuring neutralising antibodies as well as immune memory in travelers vaccinatedpreviously (> 10 years ago) with yellow fever vaccine, an assessment of the duration ofvaccine induced immunity can be made.2) To provide the…
To identify risk factors for injuries in novice runners, and to identify risk factors for specific injuries.Secondary Objective(s): 1. To determine the incidence of running related injuries in novice runners2. To describe the health benefits of the…
In one third of subfertile couples male subfertility is diagnosed. Current treatments for male subfertility, IUI, IVF and ICSI, have,despite their widespread use, not been compared on their cost-effectiveness. The primary aim of this project is to…
The primary objective of the study is evaluating the safety, tolerance and anti-lymphoma activity of the anti-CD79b-MMAE conjugate (DCDS4501A) and the anti-CD22-MMAE conjugate (DCDT2980S), both given in combination with Rituximab once every 4 weeks…
The objective of this cross-sectional study is to assess the relation between plaque characteristics, detected by Coronary Computed Tomography Angiography (CCTA) and Intravascular Optical Coherence Tomography (IVOCT), and the hemodynamic…
The main objective is to determine the effect of different anticoagulant and procoagulant agents on thrombin generation in whole blood and compare it to the effect on thrombin generation in PPP and PRP at different tissue factor concentrations. In…
Primary Objectives:The primary objective for this study is to evaluate the proportion of subjects who achieve SVR12 (HCV RNA < LLOQ (target not detected) at post-treatment follow-up Week 12 in subjects with GT-1b, -4 and GT-2, -3.Secondary…
The goal of this study is to investigate the feasibility of the integration of an EMTS in a standard clinical EUS setting.
The primary goal of the study is to evaluate the effect of CAT on daily functioning and community participation, and thereby psychosocial well-being. Secundairy goals are evaluating the implementation of CAT in the usual care and eveluation of the (…
To detect the differences in the length of the urethra in healthy volunteers and in men after laparoscopic radical prostatectomy.To detect the degree of erectiel dysfunction before and after laparoscopic radical prostatectomy.To detect the cause of…
The primary objective of the ERY-PAO study is to investigate the pharmacokinetics of acetylsalicylic acid (ASA) and omeprazole in morbidly obese subjects before and after RYGB surgery and to compare these data to study if there are differences in…
Primary Objective: Using task fMRI to assess differences in the brain activation during evaluative social feedback and script-driven emotional imagination between participants with BPD and healthy controls. Moment-to-moment self-esteem and mood…
Objective(s): The primary objective of this study is to asses the dynamic vaginal pressure profile in two groups: 1) women diagnosed with dyspareunia and, 2) women with primary vaginismus. The secondary goal is to assess vaginal reflexes in women…