110 results
To determine if maintenance treatment with lenalidomide prolongs progression free survival in patients with advanced stage CTCL that has notbeen previously treated with intravenous chemotherapy except the chemotherapy received in the preceeding…
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
The purpose of this clinical study is to provide confirmation of the clinical safety and performance of the CINCOR* System in patients at risk of developing CIN who are undergoing interventional percutaneous coronary procedures.Further, the data…
Primary goal:To investigate whether specific plaque characteristics are associated with ischemic lesions, especially (clinically silent) cerebral micro-infarcts, we will perform preoperative high resolution 3 and 7 Tesla MR plaque imaging in…
Primary Objective: Mapping the consequences of a congenital monokidney on kidney function for children with MCKD.Secondary Objective(s): - Giving recommendations about follow-up for children treated with nephrectomy for MCKD.- Defining better blood…
Primary Objective:To preliminarily evaluate the efficacy of GLPG0259 compared with placebo in terms of the proportion of subjects achieving ACR20 at Week 12 (Visit [V]7).Secondary Objectives:•To evaluate the efficacy of GLPG0259 compared with…
With this study we want to get more insight in genetic characteristics that are able to predict the susceptibility to joint damage in haemophilia patients. Therefore we want to determine the association between the (GT)n-repeat length within the…
ObjectiveInventory of the support and willingness of the visitors of the temples to participate. This study should be beneficiary in the development of a preventive program, focusing on depression. The primary outcome of this randomised trial is:…
Primary objective: to compare changes in endothelial function in patients with obesity related hypertension after 8 weeks of treatment with aliskiren, moxonidine and HCTZ.Secondary objectives: to compare changes in the following parameters in…
(1) How accurately do the TVS-CMD items reflect clinically relevant symptoms? (2) What is the concurrent and discriminant validity of the TVS-CMD? (3) How can the scoring system of the TVS-CMD be optimised?
The first aim of this study is to identify factors which predict an improvement of gastroesophageal reflux after gastric banding. The second aim is to assess the effect of gastric banding on gastroesophageal reflux after the operation.
Change from baseline in regional cerebral blood flow in response to various visual stimuli ascertained by Positron Emission Tomography scan after 8 weeks of flibanserin 100 mg treatment.
To identify intraarticular parameters related to the initiation and course of development of articular cartilage lesions after knee trauma.
2.1 Primary objectiveTo compare the wear rate 24 months after THA of HXLPE stabilized with vitamin E versus conventional UHMWPE for total joint arthroplasty.2.2 Secondary objectives1. To compare the wear rate at 3,12 and 24 months after THA between…
1. Is KJD clinically non-inferior to current surgical techniques (HTO and TKP)?2. Is KJD superior to HTO in actual structural repair of cartilage?3. Is KJD cost-effective in the long-term compared to HTO and TKP?
Part A:To demonstrate that SAR153191 on top of MTX is effective on reduction of signs and symptoms of rheumatoid arthritis at 12 weeksPart B:• To demonstrate that SAR153191 on top of MTX is effective on reduction of signs and symptoms of RA at 24…
The objective of the proposed pilot study is to explore acceptability and feasibility of structured and adequate symptomatic treatment in adult women with uncomplicated UTI.
The main objective is to assess the frequency of hidden mosaicism, including Y material, in TS patients and examine the effect on: response to different GH doses and GH injection frequency regimens, aortic diameter and distensibility, congenital…
This pilot study investigates the feasability of a randomised controlled trial investigating whether the treatment of type 2 diabetes mellitus in people of 80 years and older should be retargeted to optimise quality of life instead of blood glucose…
The major research objective is to prove that the consumption of plant stanol ester enriched yogurts can improve immune function in vivo in asthma patients