880 results
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
To assess whether children with relapsed/refractory AML, who do not achieve remission or relapse after treatment with the Relapsed AML 2001/01 standard reinduction protocol (fludarabine, cytarabine and GCSF with or without DaunoXome�), can be…
The investigational formulae are equivalent to the currently marketed control formula with regard to weight gain of healthy full-term infants during first 16 weeks of life.
H0= Saline is inferior to sodium bicarbonate for the prevention of contrast induced nephropathy in patients undergoing computed tomography after intravenous contrast administration. H1= Saline is noninferior to sodium bicarbonate for the prevention…
A high fat-diet can influence IMCL and IHL in rodents and in humans, the time-course of peripheral lipid accumulation in liver and skeletal muscle while switching from a low-fat to a high-fat diet is unknown.
A relatively high quantity of dietary protein is needed to stimulate muscle protein synthesis in elderly.
Early provision of AFOs (± 2 wks after stroke) is expected to positively affect walking impairments, mobility and activities of daily living after acute stroke compared to providing AFOs later on in the rehabilitation process (± 10 wks after stroke…
The stimulant effects of caffeine result in its common consumption by individuals in an attempt to combat the detrimental effects of fatigue on performance. However, inconsistent findings regarding the effects of caffeine on cognitive performance…
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It is expected that modafinil improves cognitive functioning in abstinent alcohol dependent patients, increases time to first relapse and reduces relapse rates and relapse severity. In addition, it is expected that participants with different…
Fatty acids supplementation can: 1. Reduce or prevent triglycerides increase; 2. Reduce inflammatory markers concentration.
In patient with clinically suspected appendicitis, imaging is needed to substantiate the clinical diagnosis. Imaging accuracy of US and CT is suboptimal, and the associated use of ionizing radiation and iodinated contrast medium are major drawbacks…
Does suppletion of vitamine D3 (cholecalciferol) have an effect on the systolic blood pressure in hypertensive, vitamin D insufficient patients? 1. H0 hypothesis: there is no effect on the systolic blood pressure; 2. H1 hypothesis: the systolic…
Smoking cessation after development of coronary heart disease improves prognosis more than any other treatment and prevents future cardiovascular diseases. This study aims to provide hospitalized coronary heart disease patients who smoke with proven…
Genestein inhibits the synthesis of heparan sulphate and can possibly slow down disease progression in Sanfilippo Syndrome patients.
It is expected that 8 days of supplementation with the study product will contribute to an improved immune response and to increased incorporation of EPA and DHA in white and red blood cells and plasma.
In the original study (NTR215), we assessed the 3-year risk of CIN3+ in women stratified for hrHPV and cytology at baseline. In this study, we will assess the 5-year risks. Stratification at baseline is done on hrHPV, cytology, and hrHPV genotype.…
Hearing aid fitting will reduce the tinnitus burden in patients with mild hearing loss.
Is docetaxel weekly as effective and less toxic than the same dose given 3-weekly.