4201 results
The purpose of this study is to determine the need for thromboprofylaxis in patients being treated in a below-knee plaster cast after trauma of a lower extremity and if there is, to assess if both of the two tested prophylactic treatments are suited…
1. To determine the diagnostic accuracy, in terms of detecting a vascular malformation, of CTA, MRI/MRA, DSA, or combinations thereof in patients with ICH?2. To find out which test or combination of tests is most effective for the detection of…
Primary: To provide insight in the prevalence of diagnosed cases of IgG-subclass and/or antipolysaccharide antibodydeficiency in Dutch children. Secondary: To provide insight in the diagnostic process, the clinical presentation, the therapies used…
To evaluate the efficacy of romiplostim for the treatment of thrombocytopenia in subjects with international prognostic scoring system (IPSS) low or intermediate-1 risk MDS as measured by the number of clinically significant bleeding events.
To document the long-term safety and tolerability of teriflunomide in MS patients with relapses.
The objective is to compare the outcome of elective surgery to conservative management for patients with persisting abdominal complaints after an episode of diverticulitis and/or frequently recurring diverticulitis (within one year).
To assess the difference in treatment effect (change between start and 6, 12, 54 and 78 months follow-up of fatigue severity and quality of life in patients with chronic fatigue syndrome) between individual multidisciplinary rehabilitation treatment…
Primary: Evaluation of the effectivity of a multidisciplinary cognitive behavioural lifestyle program combined with a Short Message Service (SMS) maintenance treatment with infertile overweight and obese PCOS women.
Aim of this prospective study is to determine (temporal changes in) the intestinal microbiota in faecal specimens and microbiota adhering to the intestinal mucosa using bacterial DNA-based profiling methods.
To evaluate the prevalence of gastrointestinal ischemia in patients with acute and chronic non-cirrhotic, non-malignant PVT.
A. Determine the placement of the Maple-probe in relation to the anatomy of the pelvic floor musculature.B. Determine the normal rest tone of the pelvic floor musculatureC. Determine the normal activity of the pelvic floor musculatureD. Determine…
Validation of CT angiography and MRI protocols to identify the different components of the atherosclerotic plaque in the carotid arteries compared to and histology.
The main objective of this study is to show the differences in outcome of two fundamentally different operational techniques in hallux rigidus. It will assess pain, range of motion and activity level in both groups using the standardised AOFAS-HMI…
Aims:a) Understand persistence and/or plasticity of the brain correlatesb) Understand specificity of the brain correlatesQuestions:a) Which neural correlates of OCD are state dependent and thus normalized after successful treatment?b) Which neural…
The assessment of the duration of the cellular immunity to Bordetella pertussis after an extra ACV booster and the relationship between the memory B- cells and antibody responses. The methods used in the study are:B- and T- cell memory responses and…
This study aims at developing a novel strategy to optimise the treatment of oesophageal adenocarcinoma and gastro-oesophageal junctional tumors with curative intent. To improve the outcome of patients with this disease we hypothesize that the…
This project aims to understand the symptomatology PD in the light of functional brain interactions, in the hope of elucidating the role of the frontal striatal system to behaviour.
Objectives: • To provide continuing treatment to subjects with SLE who complete HGS1006-C1056 or HGS1006-C1057.• To evaluate the long-term safety and tolerability of belimumab in subjects with SLE.
The objective of this study is to establish the (cost) effectiveness of transmural collaborative care including a Consultation Letter for the GP and duloxetine (TCCCL) versus Duloxetine in patients with depression that present themselves with (sub)…
To demonstrate whether using MSCT to reclassify individuals who are at high-risk based on traditional risk factors.