32 results
To investigate the correlation between androstenedion in saliva and serum in all patients that have a request for androstenedion in serum.To collect age related reference ranges for healthy children on three different time points.
The primary objective of the study is to evaluate the effect of Rebif New Formulation 44 mcg (tiw and ow) versus placebo on the time to conversion to McDonald MS in patients with a first clinical demyelinating event at high risk of converting to MS…
The first objective is to evaluate the safety of cetuximab in patients with scleroderma associated PAH. The secondary objective is to assess efficacy.
Evaluation of the approach, both volar and dorsal: By means of function of the wrist, pain scores, complications and extra surgery.
The main objective of this research proposal is to 1). develop an on-line monitor for young athletes to prevent them from a systematic overload and to avoid overtraining 2) develop clinical tools to improve diagnostics of overtraining.
Primary objective is to demonstrate that the effectiveness of thesurgical intervention with X STOPPK is equivalent to surgical decompression without fusion after 1 year after surgery.Secundary objectives are to demonstrate that surgical intervention…
In this study, the relationship between deficits within emotional memory and different typologies of psychopathy (impulsive vs. instrumental) will be examined. Furthermore, the current research concerns the influence (either positive or negative) of…
The main objective of this study is to explore the changes in the walkingperformance, while walking with the Sports Coach set at 50-70% of the maximal heart rate for chronic low back pain patients and asymptomatic controls.
Delayed cerebral ischemia (DCI) is an important cause of death and dependence after SAH. Vasospasm plays an important role in the pathogenesis of DCI, because many patients have constricted arteries during the period of DCI, but vasospasm is not a…
The objective of the study is to determine whether the HCHWA-D gene mutation affects the proteolysis of AßPP with regard to the ratio of the diverse Aß species produced from AßPP.
Primary objectivesTo establish the safety and tolerability of1. two doses of bevacizumab 7.5 mg/kg administered every 3 weeks with concurrent thoracic radiotherapy to 66 Gy;2. concurrent (7.5 mg/kg) and maintenance (15 mg/kg) bevacizumab during, and…
The main goal of neoadjuvant therapy should be a pathological complete response (pCR), because pCR more accurately predicts improved patient outcome and prolonged survival. In the present study, pathological response will be evaluated by The Miller…
Investigating the safety of adalimumab when administered in subjects with Crohn*s Disease as well as evaulating the efficacy of adalimumab for the induction and maintenance of clinical remission and fistula closure in subjects with moderate to…
The objective of the study is to ascertain whether the high effect sizes obtained in the previous studies can be explained according to our working hypothesis, i.e. whether the intervention with Urocell is associated with a structural regeneration…
In this double-blind randomized controlled trial, we would like to show that a five-day treatment course with 16mg/day oral dexamethason is effective in inducing recovery from an exacerbation of MS. The advantages of oral dexamethason over…
Is the muscle weakness during cataplexy due to pre- or postsynaptic inhibition? In other words: what happens with the H-reflex and Magnetic Evoked Potential during REM sleep and cataplexy?
Aquiring Dutch norms for the Social Fobia Scale (SFS), Social Interaction Scale (SIAS), Cognitive Scale for Irritable Bowel Syndrome (CS-FBD) and the Body Image Concern Inventory (BICI).
Purpose: Determine the ADAMTS-13 activity in patients with a history of TTP.
This pilot study will be conducted prior to initiating a large study to determine the potential dermal and inhalation exposure during pour liquid activities. This study is being conducted to test materials and methods for measuring potential dermal…
To assess properties of neuromuscular reflex performance, viz. reflexive impedance, reflex gain, reflex time delay and reflex gain modulation in patients over 65 with a positive history of falling, compared to an age and sex matched control group