516 results
The main objective of this study is to detect potential biomarkers for the differentiation of PD and DLB and the differentiation of PD subtypes by using neuroimaging.
Investigate the phenotype, function and regulation of TRM in healthy human lung tissue, lung tumors and peripheral blood to improve the understanding of respiratory diseases and adoptive T-cell therapy for lung cancer.
The primary objective of this study is to demonstrate that free field word recognition scores in quiet and noise with CI *ON* are significantly better than the best aided pre-implant scores in the ear to be implanted (contralateral ear plugged)…
This study addresses the following three questions:1. How do fear memories change over time?2. How is the context of fear coded in the brain?3. How can the process of excessive strengthening of fear memory be disrupted
Development and validation of the D-AI KIDS and the D-AI YA:Currently there is no standardized instrument that measures visually impaired children*s and young adults' participation based on the nine ICF-CY domains. The primary objective of this…
Primary Objective- To evaluate the long term safety and tolerability of treatment with CP-690,550 (10 mg BID or variable dose 5 and 10 mg BID) in adult subjects with moderate to severe chronic plaque psoriasis who are candidates for systemic therapy…
The NEURONED-MS cohort study aims to facilitate prospective observational research in the field of multiple sclerosis (MS). This cohort will serve as the central part of several projects that will be organized to address various issues including:1.…
The major objective of this pilot study is to delineate SAD endophenotypes by investigating information processing characteristics, brain activity and connectivity, within the two key dimensions relevant to the SAD symptomatology: attention and…
The aim of the present study is to investigate the reproducibility of upper extremity strength measurements in children with CP. The following strength measurement instruments will be studied: Hand Held Dynamometry (HHD), pinch- and grip strength…
Analyse the correlation between baseline MSC level in peripheral blood from cancer patients and their primary tumor type.
Primary Objective: to ascertain whether tVNS affect performance (as measured by modulation of reaction times and/or error rates) in two cognitive tasks designed to examine PES and PIA, as well as specific components of pupillary response that will…
A fundamental question in the current research proposal concerns how changes in cognitive and social-emotional behavior are related to functional and anatomical brain development. The current proposal has the objective to (a) understand the neural…
We aim to test how inhibitory processes within the primary motor cortex change over time during the resolution of response conflict.
The main objective of this study is to investigate the effectiveness of the self-help program compared to a waiting-list control group in reducing depressive symptoms. Secondary objectives include the investigation of moderators and mediators of…
We aim to measure the vitamin D status (25(OH)D) and prevalence of vitamin D deficiency in Western and non-Western infants and toddlers aged six months to four years in the Netherlands. We will assess the cross sectional association between vitamin…
Study of the phenotype and function of NK cells obtained from peripheral blood and liver of patients who are successfully being treated for at least 3-4 years for their chronic HBV infection with tenofovir in a flow-up study (METC nr. 2008-271).
The aim is to establish a correlation between sleep time and sleep efficiency, measured by actigraphy and daytime functioning (irritability, drowsiness and physical activity) of adults with a moderate intellectial disability.
We aim to provide causal evidence for the following:Study arm one: That the oscillatory brain response produced by a visual stimulus can be modulated by tonically altering cortical excitability using tDCS.Study arm two: That functionally relevant…
This study tests the ability of the Cue-shoe, a new cueing device, to provide patients with FoG with successful cueing.
Primary objective:The purpose of this study is to investigate what the changes in weight are after dietary treatment, according to the guideline 'Malnutrition in geriatric patients' in subgroups malnourished geriatric outpatients.…