923 results
To determine sensitivity, specificity, positive predictive value and negative predictive value of the spectroscopic cervical imaging device in detection of high grade cervical intraepithelial neoplasia.
Primary ObjectiveTo investigate whether ultrasound guided tumor resection succeeds gross total resection significantly more frequently, when compared with the conventional non-ultrasound guided tumor resection.Secondary Objective(s)To investigate…
The current randomized study aims to evaluate potential differences between the Edwards SAPIEN bioprosthesis and the Medtronic CoreValve® system with main focus on periprosthetic aortic regurgitation and additional focus on other clinical and…
Evaluation of the histologically proven adenoma or carcinoma detection rate in patients undergoing a full colonoscopy with and without mucosal contrast enhancement, obtained with 200 mg of Methylene Blue MMX® tablets. The lack of mucosal contrast,…
Studying the effect of two intervention programs (1. Motor Imagery Training, 2. Cognitive Orientation to Daily Occupational Performance (CO-OP)) on the motor abilities, motor imagery and motor planning capacities in children with Developmental…
The primary objective is to compare metformin versus no intervention for incidence of GDM in women with a high risk for GDM. The main secondary objective is pregnancy outcome with Metformin, neonatal outcomes and neonatal complications.
EFFICACY OBJECTIVESThe primary efficacy objective of this study is to evaluate the efficacy of intravitreal injections of 10 mg lampalizumab administered Q4W or Q6W in CFI profile biomarker positive and CFI profile biomarker-negative patients…
The aim of this study is to compare the additional diagnostic yield (adenoma detection rate) of G-EYE colonoscopy with that of standard high definition colonoscopy.
This study aims to provide a more rational evidence base for appropriate management for metastatic melanoma in the groin LNs, through assessing the effect of the addition of ipsilateral pelvic lymphadenectomy on patient disease-free survival (DFS),…
To assess visibility of standardized induced bruises using imaging (photography) under white light, forensic light sources, and multispectral scanning, at set time intervals.To gain understanding in the influence of individual factors on bruising.
The primary objective (on lesion-based analysis) is to show that pre-treatment 89Zr-trastuzumab PET/CT is able to select lesions not responding morphologically from treatment with T-DM1 (applying RECIST 1.0 criteria)Secondary Objectives and…
The aim of this pilot-study is to examine the accuracy of MRL compared to current nodal staging methods. We expect anacceptable accuracy of the MRL based on earlier studies with gadofosveset enhanced MRI in rectum cancer patients. Then the MRL could…
Primary objective of this study is to assess changes in brain connectivity and activity in the Default Mode and Salience Network (hypothalamus, prefrontal cortex, nucleus accumbens, Ventral Tegmental Area) after different sugars and sweeteners.
RESEARCH QUESTION(S): Can in vivo reflectance confocal microscopy (RCM) correctly identify the subtype of basal cellcarcinoma (BCC)?Primary Objective: To study whether in vivo reflectance confocal microscopy (RCM) can correctly identify the subtype…
The main purpose of this study is to assess whether MRI-targeted biopsy can detect a similar amount of cancer as 10-12-core TRUS biopsy.
1a. Determine whether the effect of low-molecular-weight heparin can be explained by aspirin resistance. 1b. Assess the consistency of aspirin resistance during and after pregnancy measured with several complementary devices. 2. Determine…
Primary objectives: To examine the ability of functional imaging signal changes over the course of treatment to distinguish patients with and without local recurrenceSecundary objectives:To examine the correlation between the different imaging…
Primary objectiveTo evaluate the efficacy of low dose intravenously lidocaine in comparison with placebo in terms of pain relief after the first oxaliplatin administration measured by a numeric rating scale (NRS 0-10).Secondary objectives1.…
The purpose of this study is to research the influence of vibration on the neck muscles on JPE and the effect of aging on this parameter in patients with a-specific neck pain. The second purpose is to research the influence of vibration on the neck…
1) To determine whether or not a SN procedure in patients with OC is feasible through injection of the tracers in the ovarian ligaments, when the ovarian tumour has already been resected.2) To determine if blue colorization of the sentinel nodes is…