2057 results
We hypothesize that induction of labour in patients with gestational hypertension, deteriorating chronic hypertension or preeclampsia between 34 and 37 weeks reduce the maternal morbidity but might increase the RDS rate in neonates, compared to…
The purpose of the activity and heart rate monitor is to measure and track movement (acceleration) and heartbeat, and derive a number of health-related parameters, which can serve as basis for behavioral change programs leading to e.g. a healthier,…
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
Synflorix (PCV10) and Prevenar-13 (PCV13) are comparable in inducing cellular and humoral immune responses in Dutch infants for the 10 overlapping serotypes in the vaccines. Differences are expected for three serotypes that are present in Prevenar-…
The aim of this study is to pass of the care for patients with fibromyalgia more efficiently through the cooperation of the rheumatologist and the nurse specialist. Because of this, the rheumatology outpatient department can be relieved partly,…
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
Cap-assisted colonoscopy may improve the adenoma detection rate in CRC screening participants.
A nutrient dense infant formula promotes growth more effectively than current practice.
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
Tumor-positive lymph nodes in patients with early EAC can be accurately detected through a sentinel node procedure.
Frequently people experience nausea and vomiting following surgery. There are several pharmacologic interventions possible; there is no rational evidence-based approach available. In this study the current therapy regaring PONV and its efficacy in…
The scientific hypothesis of the present study is that supervised implementation of the guideline “Oral health care in (residential) care homes for elderly people” is more effective in improving oral health and oral health care of the residents when…
Use of IBD-live for 1 year: 1. Reduces the relapse rate from 40% to 25%; 2. Increases quality of life (assessed with the IMPACT-III questionnaire).
We hypothesize that liraglutide treatment, initiated before cardiac surgery, is effective in lowering the number of patients needing perioperative insulin adjustments and reducing the total amount of insulin needed in the perioperative period when…
We hypothesize that podocyturia is an early marker of ongoing renal damage during angiogenesis inhibition.
A high protein diet and resistance exercise have a positive effect on fat free mass, fat mass, muscle strength, physical functioning and quality of life compared to regular dietary and exercise advice according to CBO guidelines for treatment of…
Quantification of mast cell density in human volunteers will inform future interventional studies that impact mast cell proliferation and/or turnover
The detection rate of the ICG method to identify the SLN in breast cancer patients is not inferior to the standard 99mTc method.
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…