404 results
Given the significant number of patients with OIPN and the possible prophylactic properties of venlafaxine, this study is designed. This study will consist of a randomised placebo-controlled clinical trial to study the prophylactic effect of…
Primary objectives: To evaluate the expression of inflammatory cytokines in HS lesional skin at week four (t=4) and week sixteen (t=16): - of subjects receiving apremilast compared to subjects receiving placebo;- within both groups relative to…
In this study we are interested in the effect of high velocity low amplitude thrust manipulation at the cervical-thoracic junction and thoracic-lumbar junction in healthy elite female water polo players on :maximum throwing speedfunctional movement…
The primary objective of this study is to assess the renal safety of CSL112 in subjects with moderate RI and AMI after administration of up to 4 weekly infusions of CSL112.The secondary objectives of the study are:1. To further characterize the…
Our objective is to use magnetic resonance imaging (MRI) to investigate the neural changes after repeated transcranial direct current stimulation during an episodic memory task in patients with mild cognitive impairment and in healthy age-matched…
To investigate the potential of a novel dietary substrate preparation to enhance muscle mitochondrial function in GSD IIIa via acute nutritional ketosis. Secondary objectives are to further investigate in vivo exercise tolerance and intramuscular…
The aim of the study is to examine whether intranasal oxytocin enhances beneficial effects of social support during stress
Metformin and hydrochlorothiazide attenuate polyuria in patients treated with tolvaptan
The purpose of the activity and heart rate monitor is to measure and track movement (acceleration) and heartbeat, and derive a number of health-related parameters, which can serve as basis for behavioral change programs leading to e.g. a healthier,…
We hypothesize that liraglutide treatment, initiated before cardiac surgery, is effective in lowering the number of patients needing perioperative insulin adjustments and reducing the total amount of insulin needed in the perioperative period when…
Tranexamic acid reduces the necessity for surgery and increases quality of life.
A study to validate the results from two RCTs that SCS is indeed capable of treating otherwise refractory diabetic neuropathic pain. In addition, we will evaluate the effects of burst stimulation settings in this patient group.
1. Leadless Pacemaker (LP) therapy is superior to current standard-of-care (SOC) with regard to procedure-related complications in Transcatheter Aortic Valve Replacement (TAVI) patients who develop conduction abnomalies (CA). 2. LP therapy reduces…
Common colds have a significant impact on individuals, health care and economy. Functional food ingredients can reduce incidence, duration and severity of common respiratory tract infections in healthy elderly and adults. We hypothesize that test…
Our primary hypothesis is that treatment with haloperidol will result in more days alive without delirium or coma during the study period of 14 days. Secondary outcomes are related to delirium and include: mortality, cognitive and functional…
Faecal transplantation from a healthy donor can restore the dysbiosis present in adolescents with refractory IBS, thereby inducing improvement of the IBS complaints.
It is hypothesized that the ingestion of plant based proteins will result in a similar muscle protein synthetic response compared to animal based proteins.
Daily protein supplementation during long-term endurance exercise training augments the physiological adaptations to endurance exercise training.
A. Rocuronium will induce impairment of carotid body function through blockade of cholinergic neurotransmission in carotid bodies resulting in a reduced or absent ventilatory response to isocapnic hypoxia. B. Sugammadex will completely restore…