32 results
Is the duration of Procalcitonin guided antibiotic therapy shorter than standard antibiotic therapy in patients with sepsis admitted to the ICU and treated with antibiotics
Objective: Main object Does warming of oxaliplatin, during the two hours infusion period, reduces the acute peripheral neuropathy complaints of patients with a colo-rectal tumor more than 50% in comparison with the standard treatment?Secondary…
The purpose of this clinical investigation is to describe the safety and efficacy of the Rheos Baroreflex Activation Therapy System in subjects with diastolic heart failure.
Improve the quality of red blood cells used for cardiopulmonary bypass for neonates and infants with a bodyweight smaller then 10 Kg.
This study contributes to determine if an integrated treatment for depressed elderly could be of value for depressive elderly. When this is the case, the systematically gathered data in this research, can be used and be part of the protocol of…
This study contributes to determine if an integrated treatment for depressed elderly could be of value for depressive elderly. When this is the case, the systematically gathered data in this research, can be used and be part of the protocol of…
To test if viewing a medical consultation on video leads to comparable psychological and physiological responses to the communication as being a patient in that consultation.
1.) First, we hypothesize that a reduction of myocardial damage explained by lower levels of myocardial damage markers (e.g. troponin I, CK-MB) by sevoflurane may be related to a reduction of inflammatory mediators (i.e. TNF-α, CD11b/CD18 cells, and…
The effects of four dosages of ethanol on simulated driving performance and event-related potentials
Investigating the effects of alcohol on simulated driving and the effects of alcohol on attentional processes during driving, indicated by ERPs recorded during an auditory oddball task presented during driving and non-driving.
Objective is to compare the two groups whether the pain scores are at least the same. Also will be noticed if the incidence of side effects of morphine intrathecal are less (e.g. itching, nausea and/ or vomiting and urine retention, although this is…
The objective of this randomized, blinded, multicenter, controlled study is to compare the performance of the IBV* Valve System (treatment group) to a control group receiving a sham bronchoscopy procedure without valve placement
treatment of overweight persons with insulinresistance with a low dose metformine add to yoghurt The early reduce of glucose especially the postprandial will hopefully decrease this process. This reduce of the glucose only needs to be 1 mmol and we…
Our aim is to optimize treatment for patients with moderate to severe psoriasis by creating evidence for the optimal dose of MTX (on short- and long-term) with the largest disease reduction and the least side effects.
To compare in a randomized controlled trail (RCT) the risk of neonatal hyperbilirubinaemia between neonates treated with CFT and amoxicillin-clavulanic acid (augmentin, AUGM) combination versus neonates treated with the aminoglycoside, tobramycin (…
Primary objective: To create diagnostic and treatment tools for navigation ability in stroke patients, that can be used in clinical practice.Secondary objective: To increase knowledge about the cognitive structure and neuroanatomical correlates of…
The primary objective of this current project is to study the (cost-) effectiveness of Motivational interviewing in non-specific musculoskeletal chronic pain patients who are indicated for pain rehabilitation treatment. It is hypothesized that an MI…
2.1 Primary objectiveTo compare the wear rate 24 months after THA of HXLPE stabilized with vitamin E versus conventional UHMWPE for total joint arthroplasty.2.2 Secondary objectives1. To compare the wear rate at 3,12 and 24 months after THA between…
1. Is KJD clinically non-inferior to current surgical techniques (HTO and TKP)?2. Is KJD superior to HTO in actual structural repair of cartilage?3. Is KJD cost-effective in the long-term compared to HTO and TKP?
The primary objective of the study is:- to establish the safety and feasibility of infusion of escalating doses of autologous ASC in end-stage renal disease patients. Secondary objectives are:- to determine the effect of ASC infusion on kidney…
We aimded to investigate if there excist transdermal magnesium absorption.