139 results
The objective of this study is to investigate whether the differences in DNA methylation between individuals who were exposed in utero to the Dutch Hungerwinter (F1) and their non-exposed, same-sex siblings (F1) - as identified in epigenome-wide…
In an effort to collect safety and effectiveness information on the stent, Medlogics is conducting the Cobra II study.
Primary objective• To validate the potential of Vasovist®-enhanced MRI for accurate prediction of nodal status in patients with primary rectal cancer using histopathological examination after surgery as the SOR.Secondary objectives• To compare the…
The primary research question is:-What is the influence of cognitive functioning on on the quality of life after SAH on the long term?Two secundary research questions are:-Is there a specific neuropsychological profile after SAH on the long term?-…
To determine the performance (safety and effectiveness) of miniaturo*-I for the treatment of urinary urge incontinence.
The purpose of this study is to determine whether there is a superiority in efficacy of the sequential combined treatment Traumafocused Therapy preceded by Well Being Therapy versus the control group. The control group receives interventions focused…
To screen two different formulations of the recombinant malaria vaccine PfLSA-3-rec, one adjuvated with aluminium hydroxide and one with Montanide Isa 720, by assessing the safety and immunogenicity (phase I) profile of each formulation in humans,…
We hypothesize that endoscopic combination therapy, including in- and excision of the stenotic fibrotic ring combined with steroid injections and bougie dilation, is more effective than standard repeated endoscopic bougie dilation.
To determine if treatment with rhEPO reduces the need for top-up transfusions in neonates with red cell alloimmunization treated (with or without intrauterine transfusions).
Objective of the study: The research aims to 2 new forms of treatment for patients with comorbid PTSD as a result of multiple and repeated abuse in childhood to assess and compare Imaginary Exposure. The expectation is that these new forms of…
Treatment of small saphenous vein incompetence with MOCATM is associated with anatomical success not inferior to radiofrequency ablation.
• We expect more functional improvement and a higher level of quality of life 3 and 6 months postoperatively for patients undergoing an isolated bicesptenotomy (measured with: WORC, RAND-36, EQ-5D-5L, VAS pain, CMS, glenohumeral range of motion). •…
Contrast-enhanced ultrasound with microbubbles will localize the same axillary lymph node as Technetium-99m nanocolloid.
Percutaneous, ORIF and conservative treated of displaced intra-articular calcaneal fractures have a similar outcome as measured with the AOFAS (American Orthopaedic Foot and Ankle Society) score.
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The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
Neutralizing antibody titers after fractional dosing of yellow fever vaccine are comparable to standard dose vaccination, ten years after primary vaccination
The goal of this study is to identify and validate recently discovered and novel biomarkers of pathophysiology, diagnosis, classification, disease activity, prognosis, treatment susceptibility, and treatment efficacy in chronic inflammatory…
There is non-inferiority on return to work between moderate (40-hour) and extensive (100-hour) vocational rehabilitation, and there will be differences in cost-effectiveness in favour of the moderate program.
Online coaching modules and wireless biometric measurements have surplus value in addition to standard coaching program after bariatric surgery