The primary research question is:-What is the influence of cognitive functioning on on the quality of life after SAH on the long term?Two secundary research questions are:-Is there a specific neuropsychological profile after SAH on the long term?-…
Source
Brief title
Condition
- Aneurysms and artery dissections
Synonym
Research involving
Sponsors and support
Intervention
No registrations found.
Outcome measures
Primary outcome
Primary outcome measure: Quality of life
The main purpose of this present study is to asses the relation between
cognitive functioning and quality of life. To asses the multi-dimensional
character of quality of life we used two different measures, the first measure
is an illness-specific questionnaire, namely the Stroke-Specific Quality of
Life (SS-QOL). The second measure is a generic measure for subjective
well-being, the Life Satisfaction 9 (LiSat9), which contains 1 question about
general satisfaction about life and eight questions about satisfaction of
specific domains. Both measures will be used as outcome measures
Secondary outcome
Cognitive functioning:
With testresearch we will explore the cognitive functioning of the SAB-patient
on the most important cognitive domains, namely general functioning, language,
verbal memory, non-verbal memory, executive functioning and visuo-perception
and construction. Each domain will be represented by a domainscore. Besides
that an overall score of cognitive functioning will be created for each
patient.
Cognitive complaints:
This information is gathered by means of the Cognitive Failure Questionnaire
(CFQ). This questionnaire measures in which amount somebody experiences
cognitive mistakes (like forgetting things).
Background summary
Clinical experience and other studies showed that patients with Subarachnoid
Hemorrhage often experience cognitive and psychological problems despite a good
physical and neurological recovery on the long term. These problems seem to
effect the so called quality of life.
Most studies focused on cognitive and psychological functioning shortly after
SAH. This study shall focus on cognitive functioning and its influence on
quality of life 1,5 to 4 years after SAH. A better understandig of the
cognitive problems is desirable for arranging the best care with the best
possible result for patient as his environment. This study is built up of 2
different parts. One part consists of different questionnaires. METC Utrecht
decided that the study doesn*t fall within the scope of the Law of Medical
Research (WMO).
The neuropsychological examination consists of a semi-structured interview for
examining cognitive complaints and different validated neuropsychological tests
selected on the basis that they tapped functions that have been found in other
studies to be most sensitive to subtle cognitive impairments in patients with
SAH.
Study objective
The primary research question is:
-What is the influence of cognitive functioning on on the quality of life after
SAH on the long term?
Two secundary research questions are:
-Is there a specific neuropsychological profile after SAH on the long term?
-What is the relation between cognitive complaints and cognitive functioning?
Study design
This research is a cross-sectional study.
Study burden and risks
There will be no risks.
The semi-structured interview will take 10 minutes. After this the testresearch
will be presented which consists of validated neuropsychological material and
wich will take about 75 minutes. The research will take place at the polyclinic
in UMC Utrecht. For the trip to Utrecht the patient will receive travellingcost.
When it*s impossible for the patient to visit the polyclinic the researchers
will make an appointment for a housevisit.
Nederland
Nederland
Listed location countries
Age
Inclusion criteria
-All patients who were admitted and treated for an Subarchnoid hemorrhage caused by an aneurysm at UMC Utrecht and who are registered in the SAB database
of Trialbureau Neurology of UMC Utrecht and who gave written permission to be invited for neuropsychological examination.
gave written
Exclusion criteria
- primary infarct or hemorrhage
- not enough knowledge of the Dutch language
- other invalid permorbid impairments with consequences for the Daily Life (ADL) or of influence on cognition
-an age outside the range of age 20 to 80.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL16422.041.07 |