1205 results
We expect that the disproportionally strong clinical effects of fingolimod in relapsing remitting multiple sclerosis can be explained by enhanced functional adaptation mechanisms of the brain and that enhanced functional adaptation will be sustained…
The combination of body brace interface pressure measurements and quality of life questionnaires will improve brace treatment in patients with idiopathic scoliosis
Cast treatment is not inferior to surgical open reduction and internal fixation in terms of patient related outcome measurements.
We expect that irrational thoughts and maladaptive coping strategies will be positively changed. As a consequence of this intervention, there should be a significant decrease of: 1. The amount of cyber bullying victims; 2. The psychosocial problems…
The incidence of pulmonary embolism at autopsy in cancer patients is substantial
In this pilot study we want to look at different aspects of radiation damage, including effects on microvasculature, blood-brain barrier function and white matter changes. We hypothesize that combining these different imaging modalities (MRI and PET…
Oral deuterated water dosing can be used in septic ICU patients to study long-term diurnal muscle protein synthesis rates
Protein Supplement, used for extremely-low-birth-weight (ELBW) infants (< 1000 g) in addition to human milk and/or preterm formula in daily practice, is well tolerated and safe.
1. QEEG markers can differentiate a developmental disorder, in this case ADHD and ASD, not only from a control group but also from each other; 2. QEEG markers are associated with the change in behavioural characteristics after administration of…
To dermine the kinetics and spectrum of tumor mutations in the urine and plasma of bladder cancer patients receiving neoadjuvant chemotherapy for locally advanced cancer or systemic therapy for metastatic disease.
1. Prosthetic valve characteristics (type; location; size resulting in the presence/absence of PPM) are related to functional outcome and quality of life; 2. The incidence/spectrum of prosthetic valve-related complications in adults with CHD differs…
We hypothesize that in current dermatological practice, there is a undisclosed burden of psoriatic arthritis in psoriasis patients. We wish to discover the prevalence of known and unknown arthritis in these patients, and find clinical and…
Patients who undergo aortoiliac surgery for occlusive disease have higher rates of SSI compared to aneurysmal disease.
To study's primary objective is to establish the effectiveness of a low-threshold guided self-help intervention targeted at improving one's self image in people with anxiety and/or depressive symptoms and low self esteem. We expect to find…
Otosclerosis is an isolated ear disorder which can cause hearing and balance impairment. The cause of these symptoms is a disturbed bone metabolism confined to the area of the otic pit, the embryologic predecessor of the inner ear. Most patients…
The Rotterdam Daily Exercise Project leads to less overweight, improved fitness, healthier food habits and healthier exercise habits.
To evaluate the cost-effectiveness of therapies for male subfertility.
Health outcomes for people at risk of or suffering from non-communicable lung diseases in low-resource settings will be improved by developing capacity for implementation of evidence-based interventions for prevention, diagnosis and treatment in…