23 results
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
To assess the prevalence of LDL-C >1.8 mMol/L in a subgroup of very high risk patients with ASCVD, who remain at a very high-residual risk for ACS, despite treatment with high-intensity statins in combination with ezetimibe. This subgroup of…
The study will address the feasibility of the shared decision-making (SDM) intervention by (1) analysing the acceptability of the intervention by users (i.e. professionals and patients); (2) assessing the level of implementation; (3) testing…
We hypothesise that endoscopic sphincterotomy before biliary fully covered self-expandable metal stent (FCSEMS) placement may reduce the occurrence of post-ERCP pancreatitis by widening the orifice of the major duodenal papilla and reducing…
We hypothesize that high carbohydrate intake with sucrose will fully replenish liver and/or muscle glycogen repletion within 12 hours after exhaustive exercise in healthy well-trained endurance athletes
As changes in gutmicrobiota composition could play a role in the development of autoimmune diseases including hypothyroidism, we will investigate whether repetitive fecal transplantation from either allogenic (healthy) or autologous (own) fecal…
Transcutaneous pulsed radiofrequency (tPRF) may affect tumor activities.
The quality of life of adult patients with NMD can be enhanced by providing capability care in comparison to usual care.
The two objectives of this study are: 1) validation of two questionnaires, the Misophonia Screening List - Child and Youth and the Amsterdam Misophonia Scale-Youth (AMISOS-Y), in order to screen adequately for misophonia 2) testing the effectiveness…
The experimental treatment (game-supported TPM training) will contribute to a more effective generalisation of compensatory strategies to untrained tasks as compared to the active control group (CogniPlus training).
This study will evaluate if a pre-colonoscopy consultation at the outpatient clinic can be replaced by an eHealth tool for FIT positive participants who are referred for colonoscopy.
As this is an explorative design, no formal hypothesis is made. However, our sample size is based on a difference of 2.5% or more in cumulative incidence of serious infections when continuing IA, hypothesizing that patients who continue their IA in…
Objective: Our primary objective is to investigate whether proton MRI can be used to supply us with new relevant information regarding the small airways and lung mechanics that cannot be obtained with functional tests. This new information might…
PCT-guided treatment regarding antibiotic use is non-inferior to usual care consisting of prednisolone and or antibiotics, in terms of treatment failure at day 30 for patients hospitalized because of an acute exacerbation of COPD (AECOPD).
Primary objectives: 1. Assess the feasibility of FMT in PD patients. 2. Assess the safety of FMT in PD patients. Secondary objectives: 1. Explore whether FMT leads to alterations in motor complications (fluctuations or dyskinesias) and…
Our primary objective is to compare the effectiveness of NACD and ESWT for patients with calcifying tendinitis of the shoulder. Our hypothesis is superiority of NACD or ESWT above the other treatment in functional recovery over a period of 12 months…
The use of an interactive web-based Decision Aid reduces decisional conflict and increases patient satisfaction with information and care.
Primary Objective: To investigate whether timely delivery of iCBT will lead to a significantly lower mean fatigue severity score (CIS-fatigue) across follow-up visits (T1 and T2) as compared to care as usual. Secondary Objectives: To investigate…
We hypothesize that implementation of ambulatory cPNB for postoperative analgesia in lower limb surgery will be non-inferior regarding patient-reported overall benefit of analgesia, when compared to standard care for pain control using sPNB and…