16 results
Evaluation of acute joint damage immediately after a joint bleed in patients with haemophilia, by use of a panel of state-of-the-art biomarkers of cartilage and bone turnover measured in blood and urine. The question that will be addressed is…
Evaluation of the safety and efficacy of bortezomib combined with cyclophosphamide and dexamethasone for induction and maintenance therapy.
To test the hypothesis that IVIG treatment diminish the risk of development of chronic disease, we designed a prospective clinical intervention study in children with newly diagnosed ITP.
Primary Objective: (diagnostic)• Does MRI detect structural changes of haemophilic arthropathy in knees and ankles undetected by the Pettersson score and HJHS? (Research question 1 a & b)Secondary Objective(s): (prognostic)• Can MRI predict…
Primary:To demonstrate the safety of AMG 531 in severely refractory thrombocytopenic subjects with ITPSecondary:To monitor hematological responses to AMG 531To provide open-label use of AMG 531, and to investigate its utility in severely refractory…
The objectives are to:A. Identify subjects with VWD who may benefit from prophylaxis by determining patterns of bleeding prior to evaluation for enrollmentB. Study the effect of prophylaxis on bleeding frequencyC. Establish optimal treatment…
To improve the steady hematopoiesis post-ASCT by infusing the autologous transplant directly in the bone marrow compartment.(protocol page 6)
To reduce postoperative blood loss by improving platelet function in autologous blood donation
1. To establish the prevalence of PH in our population of children with SCD by standardized echocardiography; 2. To investigate the predictive value of alveolar and bronchial FeNO for PH in SCD patients. 3. To establish (genetic) risk factors for PH…
The primary objective of the study is to determine the gain in effectiveness of TE compared with P when applied to remove excess iron during maintenance therapy of HH patients.
The objectives of this study are to gain new insights on [1] the cause of a higher clopidogrel resistance in DMII patients[2] the increased production of tissue factor in monocytes in DMII patients
To assess whether increasing low hemoglobin levels to near normal accelerate functional recovery and shorten the revalidation period after hip fracture surgery in the elderly.
The objective of the study is to gain new insights in the causes of a higher clopidogrel resistence in type II diabetes mellitus patients
our main objective is to determine whether additional folic acid to ferrous fumarate contributes to the increase of haemoglobin and the improvement of health status in post partum anaemia. Our second objective is to asses what the difference in…
PrimaryTo assess the prevalence of anti-efalizumab positivity in two sub-populations of psoriatic subjects trated with Raptiva® in the framework of the CLEARESTTM study:- Subjects developing adverse events (AEs) corresponding to pre-specified newly…
The aim of the project is to investigate the effects of five contrasting air pollution scenarios on respiratory and cardiovascular health of young healthy volunteers.