115 results
Investigate anatomy, kinematics, clinical outcomes, and functional outcomes in Madelung deformity patients.In this study we will answer the following 3 questions:1) What is the anatomical situation of the wrist in patients with Madelung deformity,…
The primary objective of this study is to evaluate the safety and feasibility of 3 months martial arts based training program for DMD patients. The secondary objective is to gain a first impression on the program*s ability to optimally use one*s…
To analyse long-term structural joint changes after knee joint distraction as a treatment for knee osteoarthritis by use of radiographs
The ProIntens study aims to evaluate the impact of an intensive dietetic care pathway on dietary protein intake and physical functioning in older adults during hospitalisation and after discharge. Process and economic evaluations will be performed
Semi-annual treatment with zoledronic acid reduces both pain and progression of structural damage in knee osteoarthritis patients with MRI-observed bone marrow lesions
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
In rheumatoid arthritis (RA) patients with insufficient response to disease modifying anti-rheumatic drugs (DMARDs) it is unknown whether addition of tocilizumab (TCZ) to conventional synthetic (cs) DMARDs has superior efficacy compared to addition…
The objective of this study is to test the feasibility, functionality and comfort of the AFO as an aid to regain the active RoM of the ankle joint in UMND patients with equinus foot. Results of the study will be used to further optimize the AFO…
The objective of this study is to accurately assess and compare migration, clinical and radiological outcome and patient reported outcomes of two TKR prostheses: the Cemented ATTUNE (S+Tibia component) Fixed Bearing Cruciate Retaining Knee System…
Primary Objective: To study the in vivo effect of coblation treatment on knee cartilage quality in patients with meniscal lesions and partial cartilage loosening of the knee.Secondary Objective: To study the relationship between knee cartilage…
Our primary objective is to compare the short and medium term (up to 6 months) clinical results in pain and function of the Bauerfeind SecuTec OA brace with only conservative treatment (no brace) in the management of patients with medial knee OA and…
The primary objective is to study the effectiveness of a single intravenous dose of 2g of cefazolin on SSIs after IR following fixation of foot, ankle and/or lower leg fractures. Secondary objectives are to study the cost-effectiveness of 2g of…
The primary goal of this study is to provide an estimate of treatment effects and patient inclusion rate to assess the feasibility of conducting a future randomised controlled non-inferiority trial to assess whether the effect of conventional RF…
Part A:To evaluate the safety and tolerability of multiple ascending doses of SRP-5051 (4 mg/kg, 10 mg/kg, 20 mg/kg, and 30 mg/kg), administered intravenously (IV) every 4 weeks, and determine the maximum tolerated dose (MTD)Part BTo evaluate…
The main descriptive and analytic objectives are: Descriptive: To gather epidemiological evidence (prevalence, incidence) about the course of the mental, musculoskeletal, neurocognitive and cardiovascular health (dependent variables) of professional…
Primary objective:To assess the long term safety and tolerability of GIVINOSTAT in patients with DMD following core protocols program and with naïve GIVINOSTAT DMD subjects , i.e. subjects screened in study DSC/14/2357/48 who met:- all the inclusion…
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
To assess the accuracy of the screw placements after using a surgical guide in patients operated for acetabular fractures. This study will learn us which screws benefit (in accuracy of the placement) from using a surgical guide.
Primary Hypothesis: - There is a difference in PROMIS Physical Function Upper Extremity Short Form (PROMIS PF UE SF) score between group A (6 weeks distraction) and group B (8 weeks distraction) at 1 year after first carpometacarpal joint…
The objective of this study is to evaluate the biomechanical effect of the newly developed rocker soles aiming to reduce the mechanical load in patients suffering with Achilles tendinopathy and plantar fasciitis. A secondary objective is to evaluate…