167 results
To assess the effectiveness of perforation and different injection therapies (autologous blood and dextrose) in the treatment of Lateral Epicondylitis of the elbow. The primary objective of our study is examining the change in pain score in the…
The main objective is measuring the initial migration with means of Rontgen Stereophotogrammetric analysis (RSA) of the press-fit cup. The secondary objective is assessing the QoL and long term survival. The hypothesis is that the press fit cup will…
Our objective is to investigate the value of a HVIGI in chronic midportion Achilles tendinopathy, using a dubbel-blind, placebo-controlled, randomised clinical trial. We expect that this study design gives us the opportunity to provide solid advise…
To study the change in joint homeostasis induced by knee joint distraction.
Primary- Phase 1: To determine the recommended dose (RD) of cabiralizumab in patients with pigmented villonodular synovitis (PVNS)/diffuse type tenosynovial giant cell tumor (dt-TGCT)- Phase 2: To estimate the objective response rate (ORR = CR+PR)…
The purpose of this study is to determine the cost - effectiveness and safety of prednisolone 5 mg / day for 2 years compared with placebo , in patients 65 and older with rheumatoid arthritis .
The OPTIMAL cohort aims to describe the quality of life and pain perception of patients after local treatment (radiotherapy and/or surgery) of metastases of the long bones, for both the entire cohort as well as for specific treatments separately.…
Objective 1. To investigate whether LECs from the skin of PsA patients, in contrast to that of PsO, are capable of inducing a homing receptor profile that favors a T-cell migratory response towards the synovial joint on skin-derived, allogenic T-…
this multicentre randomized controlled non-inferiority trial is designed to compare the short and long term outcome of patients who underwent an arthroscopic tenotomy of the long head of the biceps tendon with or without a cuff repair.
ObjectivePlease describe:• the specific goal to be reached by the study• the hypothesis to be answered by the studyThe overall aim of the study is to determine which downstream cellular and molecular pathways involved in PsA pathogenesis are…
Primary Objective:To investigate the proportion of patients with resection specimens demonstrating induction of a pathological (near) complete remission (* 95% tumor regression)Secondary Objectives:To study tumour changes to pre-operative pazopanib…
Primary objective is to investigate the effect of a multidisciplinary, goal-attained and individualized rehabilitation intervention on satisfaction regarding activities in younger KA patients (<65 years). Secondary objectives are to…
The objective of this proposal is to investigate if duloxetine is effective as a third choice pain medication for treating chronic pain in OA compared to usual care. Furthermore, we will assess the cost-effectiveness of duloxetine treatment and if…
The primary objective of this study is to compare the response rate of Pexidartinib with that of placebo per Response Evaluation Criteria in Solid Tumors, version 1.1 (RECIST 1.1) at Week 25 in subjects with symptomatic, locally advanced PVNS or GCT…
Primary: to compare improvement on the Health Assessment Questionnaire (HAQ) between HandScan guided tight control and treat-to-target treatment and the conventional ACR/EULAR remission guided tight control and treat-to-target treatment of RA after…
To determine the contribution of musculoskeletal pain to activity limitations corrected for the impact biomechanical factors (joint biomechanics, proprioception, physical fitness) and psychological comorbidity. The secondary objective is to identify…
• Assessment of clinical, radiographic and subjective outcomes after anatomic or reverse shoulder arthroplasty with SMR stemless prosthesis;• Survival analysis;• Incidence of adverse events and identification of possible risk factors for failure.
To assess the efficacy of treatment of acute ACL ruptures with the Ligamys device.
1. How does muscle overloading expressed by pain effect SB characteristics?2. What SB characteristics are associated with jaw-muscle pain?3. Are SB and psychological stress contributing factors for TMD pain?
The aim of this study is to provide continuing access to BMN 044 treatment for subjects previously treated with the study drug. The information gained from this study is expected to further characterize the efficacy and safety of BMN 044 over a…