124 results
Primary:- To test the hypothesis that the clinical effect of KJD (determined by WOMAC) is not (clinically relevant) different from TKP at 2 years post treatment (equivalence hypothesis). Secondary:- To describe and compare the clinical efficacy over…
* To study the relationship between inflammation on MRI and syndesmophyte formation with very detailedimaging methods: radiography, computed tomography (CT), 3 and 7 Tesla MRI. * To examine the time order of pathologic changes like inflammation,…
Primary Objective: To study the arginine-NO metabolism during fracture healing and dysfunctional fracture healingSecondary Objective(s): To investigate if differences or decreased arginine and NO concentrations in bone healing form a prognostic…
Primary goal of this study:1) To determin the percentage of structural damage caused by an ankle inversion trauma. 2) Investigate to which patient characteristics, anamnestic characteristics, physical examination and structural characteristics…
To evaluate the effects of intravenous iron suppletion in iron deficient PAH patients.Amendment: to compare exercise capacity and isolated muscle strength in IPAH patients and healthy controls
To determine whether the use of epinephrine saline irrigation in therapeutic shoulder arthroscopy with need for subacromial procedures should significantly increase clarity of the view.
1. To assess the effect of odanacatib 50 mg once weekly versus placebo on lumbar spine BMD over 24 months.2. To assess the safety and tolerability of odanacatib 50 mg once weekly compared to placebo.
The aim of this prospective randomized study is to compare results of plate fixation and intramedullary fixation postoperatively after two weeks and after a follow-up period of one year.
In this study we will evaluate the diagnostic value of ultrasound in patients presenting without clinical observable synovitis at firstconsultation compared to de clinical diagnosis by the rheumatologist in the 12 month follow-up of this study.
In deze studie zal de nauwkeurigheid van peroperatieve meting van de cuppositie door een nieuw ontworpen, onlangs gepatenteerd, meetinstrument worden onderzocht. In de toekomst kan, indien het meetinstrument betrouwbaar blijkt, peroperatief de…
The purpose of this study is to identify the first time-point the OMERACT RAMRIS score for the activity of synovitis is statistically significantly reduced compared to Baseline, in response to cerolizumab pegol (CZP) therapy. In addition, the early…
The main objective is to study precision control of trunk posture and associated muscle recruitment in LBP patients and healthy controls during trunk positioning tasks in which postural control is challenged, by increased dead space breathing, by…
With this study we want to get more insight in genetic characteristics that are able to predict the susceptibility to joint damage in haemophilia patients. Therefore we want to determine the association between the (GT)n-repeat length within the…
The aim of this explorative study is to develop and evaluate an exercise protocol for patients with knee and/or hip osteoarthritis and comorbidity (e.g., coronary heart diseases, heart failure, hypertension, diabetes type 2, chronic obstructive…
The primary objective in this study is to detect the presence of supra-spinal central sensitization in patients with chronic neck pain secondary to cervical facetal arthropathy. We aim to show this by comparing the pressure-pain thresholds (PPT; the…
Our primary objective is to compare the short-term (one-year follow-up) clinical results of the DePuy Delta Xtend reversed shoulder prosthesis with conservative treatment, in the management of displaced four-part fractures of the proximal humerus of…
To determine the amount of rotational instability in trochanteric femoral fractures, related to type of implant and fracture.The primary goal is to evaluate differences in fracture micromotion (i.e. translation and rotation) between different…
To identify intraarticular parameters related to the initiation and course of development of articular cartilage lesions after knee trauma.
Our primary study objective is whether visualizing and scoring of emboli is technically feasible. Secondary we want to asses the occurence and incidence of embolic events during spinal instrumentation surgery by intraoperative monitoring with TEE.…
2.1 Primary objectiveTo compare the wear rate 24 months after THA of HXLPE stabilized with vitamin E versus conventional UHMWPE for total joint arthroplasty.2.2 Secondary objectives1. To compare the wear rate at 3,12 and 24 months after THA between…