1174 results
Primary objective• To assess the effect of use of a walk-bike in IPF patients for 8 weeks on health-related quality of life, measured with the St. George Respiratory Questionnaire, at baseline, week 9 and week 18, in patients with IPF.Secondary…
Distinguishing frontal lobe epilepsy from ADHD in terms of working memory.
The Primary objective is: 1) To investigate clinical effectiveness of the glutamatergic compound memantine in paediatric patients with: - Obessive-Compulsive Disorder (OCD) GOAT-1 - Autism Spectrum Disorder (ASD) GOAT-2 with respect to symptoms of…
The aim of this study is to investigate the effectiveness of a brief computer intervention to improve body satisfcation and self-esteem in a clinical population of adolescents with an eating disorder. We will examine whether the intervention is…
Aim of the study is to gain insight in the results of a new intervention and to compare these with the results of the treatment for complex PTSD as it is now offered . It is also our goal to gain information on how patient characteristics and…
Purpose of the study is to investigate neurocognitive and behavioral development in children of morthers with epilepsy, primary school age, and who were exposed to anti-epileptic drugs in utero. Primary research questions are: 1. what is the nature…
The primary goal of the study is to examine whether fluctuations in cognitive functioning can be measured in daily life. Another goal is to study which factors influence cognitive functioning in daily life. Finally, it will be examined whether…
The main objective of the study is to investigate the muscarinic cholinergic system as a biological substrate for cognitive dysfunction in first episode psychosis patients, i.e. at onset of illness. We seek to assess whether deficits in M1…
The primary objective of this study is to examine the effectiveness of the serious game called HealSeeker for improving time management, planning and organisation and social behaviour skills of children with ADHD. The secondary objective of this…
This proposal entails a proof-of-concept study into the neuropsychological effects of memantine augmentation in a random cross-over comparison to placebo, as add-on treatment to ongoing clozapine in severely mentally ill (SMI) patients with…
This study aims to assess the acceptability and usability of the ECH system from the perspective of patients, their informal carers and their clinicians in a routine outpatient setting for patients with recurrent depressive or bipolar disorder. A…
Zie K1. NL
In the current project we will investigate multiple risk factors and their interaction in a single study design, aiming to identify different profiles associated with social withdrawal behaviour in an Ultrahigh Risk and First Episode Psychosis…
Primary Objective: Our primary objective is to test the feasibility of the online In-MINDD intervention through a primary care-based feasibility RCT. We hypothesize, that providing persons with information on their health profile and access to…
The properties of CBD, namely potential effects on variables pertaining to fear extinction and potentially on fear retention/reinstatement while having non of the problematic side-effects found in Δ9-THC, make CBD plausibly preferential over Δ9-THC…
Primary Objectives- To replicate AVP-induced inhibition of anterior cingulate cortex (ACC) activity and functional connectivity as measured by BOLD fMRI during a face matching task. - To assess the effect of RO5285119 in the modulation of AVP…
The aim of this research is, following the aforementioned theoretical framework, to investigate whether the two candidate genes in combination with EEG and fMRI markers differentiate between children that do and do not show a clinical response to…
Primary Objective: Investigate whether early valganciclovir treatment of children with SNHL of * 20 dB, unilateral or bilateral, and a confirmed congenital CMV infection can prevent deterioration of the hearing loss at follow-up (age 18 * 22 months…
The main objective of the study is to gain insight into the cost-effectiveness of BPR compared to care as usual (CAU) for patients withSMI who have a wish for change in their societal participation. Research questions:1. Is BPR (cost-)effective…
Primary Objective• To validate the existing demarcation formula (consisting of psychometric and biological markers) which predicts the sensitivity to Lybrido or Lybridos in women with female sexual interest/arousal disorder (FSIAD with or without…