247 results
The purpose of this study is to collect additional safety and effectiveness of the InnFocus MicroShunt (MIDI Arrow) in subjects suffering from primary open angle glaucoma that are inadequately controlled on maximum tolerated medical therapy with…
• To evaluate the safety of up to 3 additional courses of oral QLT091001 administered once daily for 7 days in subjects with LCA or RP caused by RPE65 or LRAT gene mutations who have been treated previously with a single 7-day course of QLT091001 in…
To compare the severity of retinopathy of prematurity (ROP) among treated infants with an untreated control population, matched for GA at birth while confirming the dose of rhIGF 1/rhIGFBP-3 is safe and efficacious.
The primary objective of the study is to compare the accuracy in toric IOL alignment when using the VERIONTM Measurement Module and VERIONTM Digital Marker for alignment of the toric IOL or the conventional manual ink-marking procedure. The…
EFFICACY OBJECTIVESThe primary efficacy objective of this study is to evaluate the efficacy of intravitreal injections of 10 mg lampalizumab administered Q4W or Q6W in CFI profile biomarker positive and CFI profile biomarker-negative patients…
We aim to investigate whether a relation between intestinal microbiota composition, mucosal integrity and translocation of bacteria into adipose tissue of the affected eye is related to the severity of Graves orbitopathy.
The objective of this study is to observe the anatomical and functional outcomes of ocriplasmin over a 6-month follow-up period.
To determine the effect of tube position in the anterior chamber on the corneal endothelium.
Primary ObjectivesThe primary objectives of this study are:* To evaluate the long-term efficacy outcomes following short-term exposure to rhIGF-1/rhIGFBP-3 versus standard neonatal care in Study ROPP-2008-01 (Section D) as assessed by ROP associated…
Long-term follow up of patients treated with limited PDT, for a symptomatic circumscribed choroidal hamangioma, in search of possible late unwanted side effects of PDT treatment and recurrence of leakage.
The main objective of this study is to evaluate the ability of the PRECIZION Presbyopia IOL to provide near, intermediate and distance vision in patients undergoing cataract extraction and intraocular lens implantation. Study outcomes will be used…
A comparison of the PR-OCT and conventional ways of examination of patients, being slitlamp biomicrsocopy combined with stand alone SD-OCT, and fluorescein / ICG angiography, or glaucoma screening.
EFFICACY OBJECTIVESThe primary efficacy objective of this study is to evaluate the efficacy of intravitreal injections of 10 mg lampalizumab administered Q4W or Q6W in CFI profile biomarker positive and CFI profile biomarker-negative patients…
The objective of this study is to evaluate the effect of different preventive strategies on the occurrence of macular edema after cataract surgery in non-diabetic and diabetic patients.
The main objective is to determine if bisphosphonate therapy with etidronate leads to stabilization or attenuation of ongoing calcification in the leg arteries as quantified by 18F-sodium fluoride(18F-NaF) PET-CT imaging in patients with PXE.…
The primary objective is to assess the IOP and MAP in sitting and side lying position in healthy subjects and in patients with NTG.
To investigate whether oral administration of dabigatran etexilate in patients with a rhegmatogenous retinal detachment leads to clinical significant dabigatran levels and thrombin inhibiting activity in the vitreous and subretinal fluid.
The objective of this study is to demonstrate the safety and effectiveness of the Hydrus Aqueous Implant for lowering IOP in patients with primary open-angle glaucoma (POAG) who are undergoing concurrent cataract surgery.
To assess whether there is a change in visual function and status of the retina after a year of intervention in subjects with early signs of Age-related Macular Degeneration.
The objective of this study is to determine the optimal background light intensity for the examination of the visual field with a perimetry test and to confirm the de Vries-Rose, Weber's and Ferry-Porters law in patients with glaucoma.