53 results
Objective: To compare the in vivo pressure responses of air-charged catheters with water filled catheter systems pressure responses during standard cystometry.
To detect the differences in the length of the urethra in healthy volunteers and in men after laparoscopic radical prostatectomy.To detect the degree of erectiel dysfunction before and after laparoscopic radical prostatectomy.To detect the cause of…
Primary Objective: To characterize the long-term safety and tolerability of AMG 416 in the treatment of SHPT in subjects with CKD on hemodialysisSecondary Objective: To characterize the long-term efficacy of AMG 416 on intact parathyroid hormone (…
The purpose of this study is to demonstrate the effectiveness of renal denervation in lowering blood pressure in patients with therapy-resistant hypertension and end-stage renal disease who are on dialysis or who have a renal transplant.
The overall aim of our study is to evaluate the management of suspected uncomplicated UTI in women presenting in primary care through use of a novel point of care test (POCT, Flexicult). This study is being carried out in 4 European networks: Wales…
The objective of the current study is to determine whether the presence of donor-specific B cell memory determines whether a patient will develop graft rejection or inferior graft function, especially in kidney transplant recipients who have donor-…
To test the efficacy of renal sympathetic denervation therapy with a special focus on preservation of renal allograft function.
We try to find a new standard within the field of ''MicroRNA'' proteins, that swim around in peoples blood and/or urine. MicroRNA's are very small proteins, that switches of genes in the cells, they are able to switch genes…
The primary objective to our study is assessing functional outcome, quality of life, and genetic mutations in patients with a cloacal malformation. Functional outcome:- Colorectal functiono Objective: assessing colorectal function through the use of…
We aim to increase patient compliance by extending the existing treatment protocol of (oral or intravesical) anticholinergics plus application of CIC with the addition of bladder pressure measurement performed at home during CIC plus access to an…
To establish in vivo sensitivity and specificity of OCT in the diagnosis of Upper Urinary Tract Urothelial Carcinoma
To study whether the existing eGFR cut-off levels for preventive hydration of < 45 ml/min or between 45-60 ml/min in combination of other comorbidity at risk of CIN can be safely lowered to an eGFR < 30 ml/min, regarsless of the…
-The primary objective of this study is to investigate the pharmacokinetics of olaparib after a single oral dose of 300 mg to patients with advanced solid tumours and mild or moderate renal impairment compared to those with normal renal function.-…
Primary aim: Does melatonin accumulate in hemodialysis patients after a treatment period with exogenous melatonin for at least 12 weeks ?Secondary aim:Will 7 days be enough to erase the accumulated melatonin?What are the pharmacokinetics of…
The objective of this study is to identify potential predictors of renal fluid responsiveness.
The goal of this study is to find out which B-cell inhibitor results in the best reduction of anti A/B antibody levels at which time interval, to make the best choice for a particcular drug in the desensitization treatment in patients receiving an…
The study will evaluate the injection of AMDC for Urinary Sphincter Repair (USR) compared to a placebo dose, with the hypothesis that one or two treatments of AMDC is statistically superior to placebo at 12 months following the initial treatment.
To assess renal sympathetic reinnervation in the kidney allograft by 123-I-MIBG scintigraphy.
The primary objective is to assess whether RD added to usual care compared to usual care alone reduces BP (24-h or average day-time SBP as determined with the use of ambulatory BP monitoring (ABPM)) in subjects with an average mean day-time SBP of…
Primary objective of the study is• To investigate efficacy and safety of different oraldoses of BAY94-8862 given once daily over 90 daysThe secondary objectives are:•To assess the effects of these doses on a compositeendpoint of death from any cause…