84 results
Critical illness, along with the lack of zeitgebers on the PICU environment, and iatrogenic influences like medication and procedures, results in disturbed circadian rhythms in critically ill children, which is important for their recovery.
The primary objective of this study is to determine the rate of recovery of the ATTUNE knee from the time of surgery at the 6 month endpoint.
This study examines the feasibility and an indication of possible effects of ZORA robot based intervention on play in rehabilitation and special education for children with severe physical disabilities.
The primary objectives are to assess the degree of OA that patients develop 10 to 15 year after a mallet finger fracture, to find out whether there is a difference in degree of OA between conservatively treated patients with and without an…
The aim of this study is to compare the effect of a postoperativenegative pressure dressing (Prevena (TM) IMS) with a standardwound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in low riks and high…
To obtain a comprehensive overview of long-term (*5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
The goal of this study is to develope and validate a non-invasive method for the age determination of bruises. This method is tested on adult volunteers. We expect differences between the healing proces of bruises in adults and children.To be more…
The goals of this study are to evaluate the initial performance, safety and functional results of the Anser; A novel intramedullary device for fixation of midshaft clavicle fractures. The primary outcome measures will be union rate, complication…
The Activation of Coagulation and Inflammation in Trauma (ACIT) study is designed to identify the clinically significant mechanisms and pathways by which inflammation and coagulation are activated immediately following major trauma, and how these…
To evaluate the safety and clinical benefit of NexoBrid in hospitalized children (0-18 years) with deep partial and/or full thickness thermal burns of 1-30% TBSA and to compare NexoBrid to standard of care (SOC).
The primary objective is to compare the haemostatic effect of VHA-guided transfusion strategy versus optimized CCT guided transfusion strategy in haemorrhaging trauma patients. The secondary objectives of the study are to determine the effects of…
The primary objectives are to assess the degree of OA that patients develop 10 to15 year after a DRF, find out whether there is there is a difference in degree of osteoarthritis between conservative treated patients with and without an indication…
The aim of the present study is to demonstrate the effectiveness of screw IMF.
Objective: The main objective is to evaluate the difference in scar quality, after skin restoration of full thickness defects treated with Glyaderm® and STSG versus STSG alone.Secondary objectives are: to evaluate the percentage of Glyaderm® take…
First objective; to document the existence and to categorize vocal fold pathology after short term intubation and to study voice related patient complaints after short term intubation. Second and third objective; to study the pattern/type of injury…
To gain insight in the effects and cost-effectiveness of the introduction of laser Doppler imaging in burn care.
The aim of this study is to determine the immediate effects of oral alcohol consumption in healthy volunteers on gut wall integrity as measured by Intestinal Fatty Acid Binding Protein (I-FABP) and Lipopolysaccharide Binding Protein (LBP) These…
Primary Objective: To determine whether it is feasible to use an ABF device to lower the amount of steps that exceed the maximum allowed force.The specific research question that the study aims to answer is:- Is it possible to increase partial…
Primary outcomeThe primary objective of the study is to evaluate if patients undergoing resurfacing of the patella during TKA show at least 10 % improvement in the Baldini score (after 24 months) compared to patients undergoing TKA without…
Primary objective:To assess the effect of implant choice (CS vs SHS) on gait pattern in patients that are >1 year after surgical treatment for a femoral neck fracture.Secondary objectives1. To assess the effect of implant choice (CS vs SHS)…