65 results
The primary objective of this study is to assess the comparative safety and efficacy ofAztreonam Lysine for Inhalation (AZLI) and Tobramycin Nebuliser Solution (TNS) in adultand pediatric cystic fibrosis (CF) patients aged 6 years or older with…
1. To identify and specify bacteria by using RT-PCR on blood and cerebrospinal fluid (CSF) in preterm infants, having nosocomial sepsis and meningitis.2. To compare RT-PCR (see aim 1) with the gold standard bacterial culture in preterm infants,…
To assess clinical parameters and biomarkers in blood and urine in predicting bacteremia, need for hospital admission, clinical and bacteriologic cure and mortality in patients with fUTI.To determine whether a 7-day duration of antibiotic treatment…
The assessment of the duration of the cellular immunity to Bordetella pertussis after an extra ACV booster and the relationship between the memory B- cells and antibody responses. The methods used in the study are:B- and T- cell memory responses and…
Technical validation of HIV antibody detection in capillairy blood sampled with the Demecal set.
1) To determine the prevalence and the sensitivity for various antibiotics of Staphylococcus aureus in the nose (carrier) of patients visiting the outpatient department of Dermatology.2) To determine the prevalence and the sensitivity for various…
Primary objectives:(1) To describe the incidence of EV and HPeV infections in Dutch children(2) To determine the major symptoms of EV/HPeV infections in children(3) To evaluate the epidemiology and symptoms of the different subtypes of EV and HPeV(4…
Primary goal:Determination of the number of MRSA-carriers among persons in the direct surroundings of a person (index) with an infection by MRSA.Secundary goal:1. To determine if and how MRSA-colonisation spontaneously (dis)appears or spreads among…
Primary objective is to evaluate the HIV-1 specific immunity after two vaccinations with the HIV-1 specific recombinant vaccinia vaccine NYVAC-B, compared to placebo. Secondary objectives are the evaluate of the change in plasma HIV-1 RNA in…
This study assesses the prevalence of CT and GC in vocational school students and assesses the validity and feasibility of the self-triagecard as a method to efficiently identify and treat CT positive youth and limit the spread of CT.
The primary objective is to study the effect of a 16-week treatment with a PPAR-* agonist versus placebo on effectiveness of subsequent standard treatment with PEG-IFN and RBV, measured as SVR, in previously non-responders or relapsers with CHC…
This study involves research and the objective of this study is to investigate the effect of esomeprzole on the single-dose pharmacokinetics (i.e., how a drug moves through the body) of telaprevir. And to obtain additional data regarding the safety…
To study the prevalence of anal intraepithelial neoplasia (AIN) by anal cytology and - histology and to determine the role of anal cytology and HPV testing in screening programmes on anal cancer in HIV-infected MSM.
To assess the effects and costs of cranberry use to prevent symptomatic UTIs in nursing home residents.
Primary ObjectiveTo establish whether saliva samples could be used as an alternative for blood samples in the therapeutic drug monitoring for gentamicin. To meet this objective, the development of a pharmacokinetic model predicting serum gentamicin…
Primary:Assessment of the effect of preventive versus on demand nutritional advice and a nutritional supplement (a daily energy- and protein-rich evening snack) on weight loss of patients receiving standard antiviral therapy with PEG-interferon in…
To decrease the incidence of sepsis after removal of central venous catheters in the neonatal intensive care unit.
It is therefore planned to study pain perception in peripheral neuropathy in the context of positive and negative emotional stimulation. Although there is a recent plea for the study of emotional modulation of pain, only one study has as yet done so…
Effectiveness of treatment with clioquinol on parasitologic eradication is being studied as well as the clinical effectiveness of eradication in children with dientamoeba fragilis infection.
Are fluconazole saliva levels representative for serum levels in children and neonates?