382 results
The aim of the project is to study the effect of COM test compounds on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
To investigate biomarkers that play a role in the induction and resolution of AD.Secondary objective: to develop therapeutic interventions (pharmacologically) based on the revealed biomarkers.
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The purpose of this study is to investigate the effectiveness and safety of riociguat (BAY 63-2521) in patients with diffuse cutaneous systemic sclerosis.
The primary objective is to compare the efficacy and safety of SD-101-6.0vs. SD- 101-0.0 (placebo) in patients with Simplex, RecessiveDystrophic, or Junctional non Herlitz Epidermolysis Bullosa.The primary endpoint is the complete closure of the…
Primary: To demonstrate the superiority of secukinumab 150 mg and/or 300 mg to placebo in subjects with moderate to severe palmoplantar psoriasis as assessed by the palmoplantar Investigator*s Global Assessment (ppIGA) at Week 16.Secondary: Efficacy…
Primary objective;Change in section and extent of treated LH after treatment with endermotherapy® and without treatment. Change in resistance and pain during injection at the right and left LH and changes in appearance aspects of LH right and left.…
The primary objective To assess the effectiveness of an intervention program, consisting of provision of skin care products and regular group feedback, on the skin condition in health care workers The secondary objectiveTo assess whether this…
To investigate the acceptability and feasibility of exercise therapy in an aquatic environment by patients after burn injury.
Primary objective- To explore the pharmacodynamic effects of topically applied IMQ (in combination with or without TS) - To identify dose-response relationship of topically applied IMQ Secondary objective- To assess safety and tolerability of…
Scar volume and POSAS score will be measured in the Verapamil group, these will be compared to the scar volume and POSAS score in the Kenacort+Verapamil group and the Kenacort group. In addition, complications/ adverse effects will be reported.
The main objective of our study is to examine whether there is an association between IT (as determined by visual irritation grading scale after SLS patch test) and HTS formation and whether IT is a good predictor for HTS formation. If so then this…
To evaluate efficacy of topical treatment with coal tar compared to topical treatment with corticosteroids in children aged 1 to <16 years with moderate to severe AD, based on the percentage change in Eczema Area and Severity Index (EASI) at…
The aim of the project is to study the effect of KY1005-2D10 on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
Primary objectives: To evaluate the expression of inflammatory cytokines in HS lesional skin at week four (t=4) and week sixteen (t=16): - of subjects receiving apremilast compared to subjects receiving placebo;- within both groups relative to…
Assess feasibility of development of skin colour independent assessment of skin AGE accumulation by measurement of skin autofluorescence in persons with dark skin
The aim of the project is to study the effect of SNA on the gene expression in psoriasis lesions. This information can establish the right formulation and dose of SNA for further research.
Primary Objective- To assess efficacy and pharmacodynamic effects of topical omiganan BID Secondary Objectives- To assess safety and tolerability of topical omiganan BID
The aim of the project is to study the effect of "CD11781/I, CD10394/101A and CD11406/B" on typical skin features of psoriasis. Thisinformation can establish the most effective compound, right formulation and dose for further clinical…
The aim of this study is to compare the effect of a postoperativenegative pressure dressing (Prevena (TM) IMS) with a standardwound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in low riks and high…