37 results
The aim of this study is to compare the effect of a postoperativenegative pressure dressing (Prevena (TM) IMS) with a standardwound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in low riks and high…
To evaluate efficacy of topical treatment with coal tar compared to topical treatment with corticosteroids in children aged 1 to <16 years with moderate to severe AD, based on the percentage change in Eczema Area and Severity Index (EASI) at…
Primary objectives: To evaluate the expression of inflammatory cytokines in HS lesional skin at week four (t=4) and week sixteen (t=16): - of subjects receiving apremilast compared to subjects receiving placebo;- within both groups relative to…
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
To obtain a comprehensive overview of long-term (*5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
Primary objectiveThe primary objective of this study is to evaluate the efficacy of bimekizumab in subjects with moderate to severe HS.Secondary objectiveThe secondary objective of this study is to assess the safety, tolerability, immunogenicity,…
Primary objective: To prospectively evaluate the lesion (AN-)count, i.e. abscesses, inflammatory nodules, and draining sinuses, in the axilla treated with MWA compared to the untreated contralateral axilla after six months.Secondary objectives: - To…
Primary objective* To characterize and monitor wound healing after a standardized, induced skin trauma Secondary objectives* To evaluate safety and tolerability of biopsy-induced skin trauma
Our primary objectives are to determine the diagnostic accuracy of handheld RCM in the diagnosing and subtyping of BCC in the head and neck compared to punch biopsy, and evaluate the associated rate of over- and understaging of BCC subtypes. In…
The primary objective of this exploratory study is to test if prophylactic use of conestat alfa decreases the frequency of angioedema attacks in patients with InH-AAE. As secondary objectives, effects on disease severity, quality of life and drug…
Investigate the stability and reproducibility of PAI when applied to the diabetic foot. Further, we aim to compare results from PAI with the currently used non-invasive blood pressure measurements.
The primary objective of this study is to evaluate the long-term safety and tolerability of Diacerein 1% Ointment for 2 treatment cycles in subjects with EBS that were previously enrolled in studies CCP-020-301 or CCP-020-101.
Primary objective1. To test the safety of cold plasma treatment: SAE in * 10% of participants, no pain (VAT * 2) and no local skin reaction: redness, blister formation, pain or itching. Secondary objectives:The effect of cold plasma treatment on : 1…
Primary Objective:Is there a difference in the cytokine profile of uninvolved skin, perilesional skin and lesional skin of pediatric psoriasis patients on topical treatment (representing mild psoriasis) and pediatric psoriasis patients on systemic…
To determine whether a potent topical CS is more effective than a mild topical CS in the treatment of children with a moderate flare-up of atopic dermatitis in primary care on short and long term.
The aim of the project is to further develop and evaluate skin disease models by investigating the synthesis and cytokine release in atopic dermatitis lesions. This information can establish the right formulation of new medicines for further in…
to evaluate whether Doxepin hydrochloride 5% cream versus a placebo cream significantly reduces pruritus in burn patients by comparing itch scores.
The aim of the project is to study the effect of CD test compounds on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
* To evaluate the effects of topically applied erythromycin and clindamycin in patients with facial AV* To explore skin and faecal microbiota in patients with AV;* To evaluate the effects of topically applied erythromycin and clindamycin on skin and…
The goal of this study is to find a threshold value for shear loading at which the IL-1a expression starts to increase. The critical value can then function as input paramter for the design of new bedding. By changing certain surface properties such…