957 results
Here, we postulate that the balance between the effect of belatacept on regulatory T-cell function and the relative insensitivity of memory T-cells for belatacept leads to donor-specific alloreactivity. We plan to study the peripheral CD28-dependent…
With this study we will investigate the effects of lumbar sympathetic blockade on ERPF and measured GFR and relative changes in non - invasive hemodynamics measured before and after continuous lumbar sympathetic blockade or splanchnic blockade in…
Extending Popliteal block duration with adding clonidine to the levobupivacaine (= standard care)
To describe the human gastrointestinal microcirculation during gastrointestinal surgery under general anesthesia and to observe whether there is a correlation between bowel microcirculation and systemic hemodynamic parameters.
The main goal of the trial is to establish whether laparoscopic incisional hernia repair is superior to conventional open incisional hernia repair in terms of cost-effectiveness. This is measured through length of hospital stay and quality of life.…
To prospectively collect and assess global safety and efficacy data on the IN.PACT Admiral* Drug Eluting Balloon (DEB) in treatment of atherosclerotic disease of the superficial femoral and/or popliteal arteries in *real world* patient population.
The goal of the study is whether to establish if application of combined cyrocompression therapy directly postoperative after hip fracture surgery results in a significant reduction in painperception en whether this reduces the morfine consumption.…
1. To implant a functional vestibular prosthesis using the ampullar *V*-approach, as developed in our own clinic.2. To investigate protocols for adjusting the vestibular implant (VI) to required settings, regarding:-- Modulation sensitivity--…
To determine whether perioperative myocardial ischemia is associated with adverse outcome in patients scheduled for major abdominal surgery.
1. Investigate whether per-operative subcortico-muscular (LFP-EMG) coherence can be used as a predictor for favourable surgical outcome in DYS and PD tremor patients undergoing DBS surgery 2. Investigate whether pre-surgical EEG-EMG-coherence and…
The primary objective of this prospective, two-arm, multicenter, post-market study is to evaluate safety through the incidence of reported device-related adverse events (AEs) through 30 days following use of the Endo GIA* Reinforced Reload with Tri-…
The main objective of this study is to define the optimal dose of fluorescent tracer for intraoperative detection of tumor delineation during breast cancer surgery.
Primary Objective: To study whether CSWI+PCA provides similar analgesia after laparotomies for HPB conditions as compared to PCEA measured as the OBAS score, a composite endpoint composed of pain score, patient satisfaction and opioid related side…
See section 2.2. of the protocol.The primary objective of this trial is to assess the safety of an uninterrupted dabigatran etexilate periprocedural anticoagulant regimen compared to an uninterrupted warfarin regimen in NVAF patients undergoing AF…
Primary objective:Increase in left ventricular ejection fraction after bariatic surgerySecundary objectives:Reduction of paracardial fat after bariatic surgeryReduction of visceral abdominal fat after bariatic surgeryReduction of hepatic steosis…
The incidence of wound complications in endovascular aneurysm repair (EVAR). VAS scores will be obtained to objectify the advances of a percutaneous approach. Cultures and wound biopsies will be obtained from every patient. Also cost-effectiveness…
The objective of the trial is to assess the safety and tolerability of i.c.v. administration of sNN0029 infusion solution at a dose of 4 µg per day delivered via a Medtronic SynchroMed® II Infusion System.
The primary objective of the study is to investigate the maximal flexion ability of the Journey II BCS total knee system one year after surgery. The secondary objective is to assess patient satisfaction, clinical, functional and radiological…
Primary outcome parameter is the amount of intra- and postoperative transfusions required. Secondary outcome parameters include intra- and postoperative blood loss, operation time, and postoperative complications and the outcome of…
To compare the effects of sacrospinous ligament fixation combined with anterior colporrhaphy versus Elevate Anterior procedure on pelvic floor function.