404 results
Evaluation of the rise in serum creatinine and the incidence of CIN following angiography in patients treated with a short hydration regime during 1 hour with sodium bicarbonate compared to a hydration regime with saline during 6-24 hours.
The research focuses on the active screening of high prevalence patients and the diagnosis of AAA. This study aims to establish an effective screening protocol and determining a higher prevalence in patients with PAD and patients with carotid…
Our overall objective is to better understand the role of regulatory B cells in disease pathogenesis and to better predict disease flares in order to individualize treatment.
The aim of this study is to compare the 16S PCR technique with standard bacterial cultures of infected vascular grafts, mycotic aneurysms and non-infected aortic aneurysms.
We have set prior to the design and implementation of this research a primary and a secondary goal.Primary goal:Testing the validity of the computer model of the coagulation cascade and the related PK / PD model of VKA and heparin for use in…
To study the protective effect of pre-treatment with metformin on flow mediated dilation after 20 minutes ischemia and 20 minutes reperfusion. If metformin treatment indeed limits endothelial IR-injury, a second study will be performed in the same…
To assess the costs and effects of tailoring the duration of elastic compression stocking (ECS) therapy after deep vein thrombosis (DVT) to individual patients needs.
Optimization of safety of risk stratification for outpatient treatment in pulmonary embolism, through randomization between Hestia approach with or without NT-proBNP measurement.
Our primary objective is to determine the effect of breast reconstruction on the risk of developing lymphedema. Secondarily, we will look at lymphedema and the correlation with 1) primary and secondary breast reconstruction, 2) the extent of…
The primary objective is to investigate if there are differences in the acute postprandial vasodilating effect between different protein sources and if these differences are associated with differences in the responses of vasodilating factors.…
Renal sympathetic denervation is currently introduced in the Erasmus Medical Center. Th objective of the current study is to 1) study the effectiveness and safety of renal sympathetic denervation in patient with treatment resistent hypertension. 2)…
Determine the potential impact of a set of cognitive games in people with cognitive difficulties after stroke.
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
- To identify the causes of inflammation of adipose tissue, liver and blood leukocytes by focusing on the contribution of the gut microbiota taking into account dietary habits and genetic background.- To assess the influence of inflammation of…
The results of these studies will provide a possible explanation for the increased risk of cardiovascular events in patients with PHA. Our study is the first to explore the hypothesis that patients suffering from PHA are more vulnerable to IR injury…
The primary objective of the study is to investigate the effect of interruption of anti-TNF-alpha therapy on endothelium dependent and independent vasodilation and the effect of intra-arterial infusion of infliximab on the endothelium dependent and…
This study has three objectives:1. To describe flow patterns in the left atrium in patient with sinus rhythm and atrial fibrillation. 2. To prospectively verify the data in patients with atrial fibrillation3. Correlation of abnormal flow patterns to…
1. Do body fatness and/or body fat distribution show a linear association withmicrovascular function in normal as well as IGT subjects?2. Is the effect of body composition on the microvasculature mediated by alteredadipokine profile, low-grade…
Te demonstrate that the use of US-accelerated catheter-derived thrombolysis in patients with recently (between 1 and 7 weeks) thrombosed infra-inguinal bypass grafts or native arteries will significantly reduce (at least 12 hours) therapy time…
The primary objective of this study is to establish a panel of markers that can be used for further research into the understanding of the pathogenesis of PTS.